Christopher R Butter

11PUBLICATIONS
12CO-AUTHORS
Biomolecular modelling and designOrganometallic chemistryCharacterisation of biological macromoleculesMolecular medicineComputational neuroscience (incl. mathematical neuroscience and theoretical neuroscience)
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Publications (11)

|Jun 18, 2024
Design and Synthesis of Clinical Candidate PF-06852231 (CVL-231): A Brain Penetrant, Selective, Positive Allosteric Modulator of the M4 Muscarinic Acetylcholine Receptor.

Christopher R Butler, Michael Popiolek, Laura A McAllister

|Oct 22, 2021
Intramolecular Ring-Opening Decomposition of Aryl Azetidines.

Guoyun Bai, Thomas N O'Connell, Michael A Brodney

|Sep 10, 2019
Molecular Transformer unifies reaction prediction and retrosynthesis across pharma chemical space.

Alpha A Lee, Qingyi Yang, Vishnu Sresht

|Sep 05, 2019
Identification and Development of an Irreversible Monoacylglycerol Lipase (MAGL) Positron Emission Tomography (PET) Radioligand with High Specificity.

Lei Zhang, Christopher R Butler, Kevin P Maresca

|Nov 28, 2018
Striatal, Hippocampal, and Cortical Networks Are Differentially Responsive to the M4- and M1-Muscarinic Acetylcholine Receptor Mediated Effects of Xanomeline.

Catherine A Thorn, Joshua Moon, Clinton A Bourbonais

|Oct 19, 2018
In Vivo Modulation of Hippocampal Excitability by M4 Muscarinic Acetylcholine Receptor Activator: Implications for Treatment of Alzheimer's Disease and Schizophrenic Patients.

Michael Popiolek, Yael Mandelblat-Cerf, Damon Young

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Frequent Collaborators

4 joint publications

Laura McAllister

4 joint publications

Michael Popiolek

3 joint publications

Michael A Brodney

2 joint publications

Lei Zhang