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Stephen W Wright

8PUBLICATIONS

34CO-AUTHORS

Proteins and peptidesCheminformatics and quantitative structure-activity relationshipsCrystallographyNatural products and bioactive compoundsMain group metal chemistry

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Publications (8)

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|May 16, 2025

Inhibiting peptidylarginine deiminases (PAD1-4) by targeting a Ca<sup>2+</sup> dependent allosteric binding site.

Leslie A Dakin, Li Xing, Justin Hall

|Feb 28, 2025

Discovery of Nirmatrelvir (PF-07321332): A Potent, Orally Active Inhibitor of the Severe Acute Respiratory Syndrome Coronavirus 2 (SARS CoV-2) Main Protease.

Jamison B Tuttle, Christophe Allais, Charlotte M N Allerton

|Sep 24, 2024

Discovery, Characterization, and Structure of a Cell Active PAD2 Inhibitor Acting through a Novel Allosteric Mechanism.

Laura J Byrnes, Won Young Choi, Paul Balbo

|Apr 17, 2024

In Retrospect: Root-Cause Analysis of Structure-Activity Relationships in IRAK4 Inhibitor Zimlovisertib (PF-06650833).

Stephen W Wright, Kathleen A Farley, Seungil Han

|Dec 20, 2023

Synthesis of Deuterated Enaminones with High Isotopic Fidelity.

Stephen W Wright

|Mar 20, 2023

Small Change, Big Impact: Reversal of Diastereoselection in Cuprate Conjugate Additions to α,β-Unsaturated Lactams and Identification of a Competing Mechanism.

Stephen W Wright, Chulho Choi, Yu Kawamata

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Frequent Collaborators

2 joint publications

Kathleen A Farley

1 joint publications

Brian S Gerstenberger

1 joint publications

Andrew Fensome

1 joint publications

Dafydd R Owen

1 joint publications

Stefan France

1 joint publications

Chulho Choi

1 joint publications

Yu Kawamata

1 joint publications

Phil S Baran

1 joint publications

Katherine L Lee

1 joint publications

Laura J Byrnes

Frequent Collaborators

2 joint publications

Kathleen A Farley

1 joint publications

Brian S Gerstenberger

1 joint publications

Andrew Fensome

1 joint publications

Dafydd R Owen

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