Amy C-H Lee

5PUBLICATIONS
20CO-AUTHORS
Biomolecular modelling and designCheminformatics and quantitative structure-activity relationshipsPharmacogenomicsGene and molecular therapyMedical molecular engineering of nucleic acids and proteins
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Publications (5)

|Sep 04, 2024
Rational Design, Synthesis, and Structure-Activity Relationship of a Novel Isoquinolinone-Based Series of HBV Capsid Assembly Modulators Leading to the Identification of Clinical Candidate AB-836.

Andrew G Cole, Steven G Kultgen, Nagraj Mani

|Jan 08, 2024
Structure-Activity Relationships and Discovery of (S)-6-Isopropyl-2-methoxy-3-(3-methoxypropoxy)-10-oxo-5,10-dihydro-6H-pyrido[1,2-h][1,7]naphthyridine-9-carboxylic Acid (AB-452), a Novel Orally Available HBV RNA Destabilizer.

Dimitar Gotchev, Bruce D Dorsey, Duyan Nguyen

|Oct 04, 2022
Safety, pharmacokinetics, and antiviral activity of the capsid inhibitor AB-506 from Phase 1 studies in healthy subjects and those with hepatitis B.

Man-Fung Yuen, Elina Berliba, Wattana Sukeepaisarnjaroen

|Nov 10, 2018
Hepatitis B Virus Therapeutic Agent ARB-1740 Has Inhibitory Effect on Hepatitis Delta Virus in a New Dually-Infected Humanized Mouse Model.

Xin Ye, Chise Tateno, Emily P Thi

|Nov 08, 2018
ARB-1740, a RNA Interference Therapeutic for Chronic Hepatitis B Infection.

Emily P Thi, Ammen P Dhillon, Andrzej Ardzinski

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Frequent Collaborators

2 joint publications

Emily P Thi

1 joint publications

Man-Fung Yuen

1 joint publications

Sang Hoon Ahn

1 joint publications

Tawesak Tanwandee