Hesham Haffez

10PUBLICATIONS
13CO-AUTHORS
Cheminformatics and quantitative structure-activity relationshipsChemotherapyMolecular targetsCancer therapy (excl. chemotherapy and radiation therapy)Biologically active molecules
Featured researcher

Get your video featured.

JoVEPublish with JoVE
Journal

Publications (10)

|Jul 17, 2026
Thiazole-Derived Dual EGFR/CDK-2 Inhibitors: Rational Design, Synthesis, In Vitro Anticancer Evaluation, Mechanistic Profiling, and Computational Binding Analysis.

|May 27, 2026
Lead Discovery via Scaffold Refinement: Structure-Guided Optimization of 1,2,4-Triazolo[1,5-a]Pyrimidines as Potent Dual EGFR/CDK-2 Inhibitors Targeting Colorectal Carcinoma.

|May 09, 2025
Synergistic effects of abietic acid combined with doxorubicin on apoptosis induction in a human colorectal cancer cell line.

Hesham Haffez, Hend H Sanad, Hassan Ebrahim

|Mar 31, 2025
Unravelling the potency of the 4-oxo-2-thioxo-1,2,3,4-tetrahydropyrimidine-5-carbonitrile scaffold with S-arylamide hybrids as PIM-1 kinase inhibitors: synthesis, biological activity and in silico studies.

Soha R Abd El Hadi, Manar A Eldinary, Amna Ghith

|Nov 20, 2023
Novel N-Arylmethyl-aniline/chalcone hybrids as potential VEGFR inhibitors: synthesis, biological evaluations, and molecular dynamic simulations.

Hesham Haffez, Nosaiba A Elsayed, Marwa F Ahmed

|Aug 26, 2022
Augmented Therapeutic Potential of EC-Synthetic Retinoids in Caco-2 Cancer Cells Using an In Vitro Approach.

Mohamed R Abdelaal, Esraa Ibrahim, Mohamed R Elnagar

Pageof 2

Frequent Collaborators

3 joint publications

Mohamed R Abdelaal

2 joint publications

Sameh H Soror

2 joint publications

Mohamed R Elnagar

2 joint publications

Hassan Y Ebrahim