Stephen Roughley
8PUBLICATIONS
36CO-AUTHORS
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Publications (8)
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|Mar 06, 2026
Exploiting a Cryptic Pocket in DsbA through Structure-Guided Parallel Synthesis and Direct-to-Biology Screening.Yildiz Tasdan, Gautham R Balaji, James Davidson
|Oct 03, 2025
Design, modular synthesis and screening of 58 shape-diverse 3-D fragments.Thomas D Downes, S Paul Jones, James D Firth
|May 25, 2023
Fragment Merging Using a Graph Database Samples Different Catalogue Space than Similarity Search.Stephanie Wills, Ruben Sanchez-Garcia, Tim Dudgeon
|Jan 27, 2023
Rapid optimisation of fragments and hits to lead compounds from screening of crude reaction mixtures.Lisa M Baker, Anthony Aimon, James B Murray
|Dec 22, 2022
Exploration of piperidine 3D fragment chemical space: synthesis and 3D shape analysis of fragments derived from 20 regio- and diastereoisomers of methyl substituted pipecolinates.S Paul Jones, James D Firth, Mary C Wheldon
|Apr 22, 2020
Design and Synthesis of 56 Shape-Diverse 3D Fragments.Thomas D Downes, S Paul Jones, Hanna F Klein
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Frequent Collaborators
4 joint publications
Roderick E Hubbard
3 joint publications
Peter O'Brien
2 joint publications
Thomas D Downes
2 joint publications
James Davidson
2 joint publications
James D Firth
2 joint publications
Frank von Delft
2 joint publications
Alison J-A Woolford
1 joint publications
Paul A Brough
1 joint publications
S Paul Jones
1 joint publications
Masakazu Atobe
