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Stephen Roughley

8PUBLICATIONS

36CO-AUTHORS

BacteriologyF-block chemistryCheminformatics and quantitative structure-activity relationshipsBiomolecular modelling and design

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Publications (8)

Sort by Publication Date:

|Mar 06, 2026

Exploiting a Cryptic Pocket in DsbA through Structure-Guided Parallel Synthesis and Direct-to-Biology Screening.

Yildiz Tasdan, Gautham R Balaji, James Davidson

|Oct 03, 2025

Design, modular synthesis and screening of 58 shape-diverse 3-D fragments.

Thomas D Downes, S Paul Jones, James D Firth

|May 25, 2023

Fragment Merging Using a Graph Database Samples Different Catalogue Space than Similarity Search.

Stephanie Wills, Ruben Sanchez-Garcia, Tim Dudgeon

|Jan 27, 2023

Rapid optimisation of fragments and hits to lead compounds from screening of crude reaction mixtures.

Lisa M Baker, Anthony Aimon, James B Murray

|Dec 22, 2022

Exploration of piperidine 3D fragment chemical space: synthesis and 3D shape analysis of fragments derived from 20 regio- and diastereoisomers of methyl substituted pipecolinates.

S Paul Jones, James D Firth, Mary C Wheldon

|Apr 22, 2020

Design and Synthesis of 56 Shape-Diverse 3D Fragments.

Thomas D Downes, S Paul Jones, Hanna F Klein

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Frequent Collaborators

4 joint publications

Roderick E Hubbard

3 joint publications

Peter O'Brien

2 joint publications

Thomas D Downes

2 joint publications

James Davidson

2 joint publications

James D Firth

2 joint publications

Frank von Delft

2 joint publications

Alison J-A Woolford

1 joint publications

Paul A Brough

1 joint publications

S Paul Jones

1 joint publications

Masakazu Atobe

Frequent Collaborators

4 joint publications

Roderick E Hubbard

3 joint publications

Peter O'Brien

2 joint publications

Thomas D Downes

2 joint publications

James Davidson

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