Ian R Outhwaite

10PUBLICATIONS
40CO-AUTHORS
Biomolecular modelling and designMolecular targetsCheminformatics and quantitative structure-activity relationshipsSignal transductionProteins and peptides
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Publications (10)

|Sep 23, 2026
A design approach for bitopic kinase inhibitors.

|Jan 31, 2024
Lucanthone, a Potential PPT1 Inhibitor, Perturbs Stemness, Reduces Tumor Microtube Formation, and Slows the Growth of Temozolomide-Resistant Gliomas In Vivo.

Daniel P Radin, Sophie Shifman, Ian R Outhwaite

|Dec 04, 2023
Death by a thousand cuts through kinase inhibitor combinations that maximize selectivity and enable rational multitargeting.

Ian R Outhwaite, Sukrit Singh, Benedict-Tilman Berger

|Oct 18, 2023
Probing conformational dynamics to understand kinase inhibition.

Ian R Outhwaite, Markus A Seeliger

|Feb 16, 2023
Allosteric regulation and inhibition of protein kinases.

Victoria R Mingione, YiTing Paung, Ian R Outhwaite

|Jan 30, 2023
Death by a Thousand Cuts â€" Combining Kinase Inhibitors for Selective Target Inhibition and Rational Polypharmacology.

Ian R Outhwaite, Sukrit Singh, Benedict-Tilman Berger

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Frequent Collaborators

7 joint publications

Markus A Seeliger

2 joint publications

Aziz M Rangwala

2 joint publications

John D Chodera

1 joint publications

Stephen Barstow Long