Ian R Outhwaite
9PUBLICATIONS
26CO-AUTHORS
Get your video featured.
Publish with JoVEGet your video featured.
Publish with JoVE
Publications (9)
Sort by Publication Date:
|Jul 31, 2024
Absence of ABL1 exon 2-encoded SH3 residues in BCR::ABL1 destabilizes the autoinhibited kinase conformation and confers resistance to asciminib.Ariel Leyte-Vidal, RosaAnna DeFilippis, Ian R Outhwaite
|Jan 31, 2024
Lucanthone, a Potential PPT1 Inhibitor, Perturbs Stemness, Reduces Tumor Microtube Formation, and Slows the Growth of Temozolomide-Resistant Gliomas In Vivo.Daniel P Radin, Sophie Shifman, Ian R Outhwaite
|Dec 04, 2023
Death by a thousand cuts through kinase inhibitor combinations that maximize selectivity and enable rational multitargeting.Ian R Outhwaite, Sukrit Singh, Benedict-Tilman Berger
|Oct 18, 2023
Probing conformational dynamics to understand kinase inhibition.Ian R Outhwaite, Markus A Seeliger
|Feb 16, 2023
Allosteric regulation and inhibition of protein kinases.Victoria R Mingione, YiTing Paung, Ian R Outhwaite
|Jan 30, 2023
Death by a Thousand Cuts â€" Combining Kinase Inhibitors for Selective Target Inhibition and Rational Polypharmacology.Ian R Outhwaite, Sukrit Singh, Benedict-Tilman Berger
Pageof 2
Frequent Collaborators
6 joint publications
Markus A Seeliger
2 joint publications
Aziz M Rangwala
2 joint publications
John D Chodera
1 joint publications
Stephen Barstow Long
1 joint publications
Hannah E Phillips
1 joint publications
Rebecca B Jennings
1 joint publications
Neil P Shah
1 joint publications
Mansi Chandra
1 joint publications
Victoria Ende
1 joint publications
Alexander A Peterson
