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Aziz M Rangwala

6PUBLICATIONS

29CO-AUTHORS

Molecular targetsCheminformatics and quantitative structure-activity relationshipsProteomics and intermolecular interactions (excl. medical proteomics)Gene and molecular therapy

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Publications (6)

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|Mar 10, 2025

Prospective evaluation of structure-based simulations reveal their ability to predict the impact of kinase mutations on inhibitor binding.

Sukrit Singh, Vytautas Gapsys, Matteo Aldeghi

|Jul 31, 2024

Absence of ABL1 exon 2-encoded SH3 residues in BCR::ABL1 destabilizes the autoinhibited kinase conformation and confers resistance to asciminib.

Ariel Leyte-Vidal, RosaAnna DeFilippis, Ian R Outhwaite

|Sep 27, 2022

Discovery and molecular basis of subtype-selective cyclophilin inhibitors.

Alexander A Peterson, Aziz M Rangwala, Manish K Thakur

|May 28, 2022

Kinases on Double Duty: A Review of UniProtKB Annotated Bifunctionality within the Kinome.

Aziz M Rangwala, Victoria R Mingione, George Georghiou

|Mar 07, 2022

Resistance to kinase inhibition through shortened target engagement.

Aziz M Rangwala, Benedict-Tilman Berger, Matthew B Robers

|Nov 09, 2021

Mutation in Abl kinase with altered drug-binding kinetics indicates a novel mechanism of imatinib resistance.

Agatha Lyczek, Benedict-Tilman Berger, Aziz M Rangwala

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Frequent Collaborators

6 joint publications

Markus A Seeliger

2 joint publications

Jiaye Guo

2 joint publications

Stefan Knapp

2 joint publications

Ian R Outhwaite

1 joint publications

Benedict-Tilman Berger

1 joint publications

Matthew B Robers

1 joint publications

Victoria R Mingione

1 joint publications

George Georghiou

1 joint publications

Alexander A Peterson

1 joint publications

Patrick S Ward

Frequent Collaborators

6 joint publications

Markus A Seeliger

2 joint publications

Jiaye Guo

2 joint publications

Stefan Knapp

2 joint publications

Ian R Outhwaite

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