Mark R Denison

7PUBLICATIONS
46CO-AUTHORS
Radiation therapyCheminformatics and quantitative structure-activity relationshipsPharmacogenomicsMedical molecular engineering of nucleic acids and proteinsMolecular targets
Featured researcher

Get your video featured.

JoVEPublish with JoVE
Journal

Publications (7)

|May 06, 2026
Loss of nsp14-exonuclease activity impairs the replication, proofreading, fitness, and pathogenesis of SARS-CoV-2.

|Sep 03, 2025
Mechanism and spectrum of inhibition of viral polymerases by 2'-deoxy-2'-β-fluoro-4'-azidocytidine or azvudine.

Hery W Lee, Egor P Tchesnokov, Laura J Stevens

|Apr 28, 2022
Mutations in the SARS-CoV-2 RNA-dependent RNA polymerase confer resistance to remdesivir by distinct mechanisms.

Laura J Stevens, Andrea J Pruijssers, Hery W Lee

|Jan 19, 2021
The coronavirus proofreading exoribonuclease mediates extensive viral recombination.

Jennifer Gribble, Laura J Stevens, Maria L Agostini

|Aug 07, 2020
SARS-CoV-2 mRNA vaccine design enabled by prototype pathogen preparedness.

Kizzmekia S Corbett, Darin K Edwards, Sarah R Leist

|Apr 08, 2020
An orally bioavailable broad-spectrum antiviral inhibits SARS-CoV-2 in human airway epithelial cell cultures and multiple coronaviruses in mice.

Timothy P Sheahan, Amy C Sims, Shuntai Zhou

Pageof 2

Frequent Collaborators

5 joint publications

Timothy P Sheahan

3 joint publications

Ralph S Baric

3 joint publications

Andrea J Pruijssers

2 joint publications

Stephanie A Montgomery