Brett Howell

5PUBLICATIONS
20CO-AUTHORS
Molecular targetsMetabolomic chemistryToxicology (incl. clinical toxicology)Pharmaceutical delivery technologiesCancer therapy (excl. chemotherapy and radiation therapy)
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Publications (5)

|Oct 09, 2026
Integrating a Tumor Size-Overall Survival Model Into a Spatial Quantitative Systems Pharmacology Framework for Antibody-Drug Conjugates in Non-Small Cell Lung Cancer.

|Jan 16, 2026
Quantitative Systems Toxicology Modeling with DILIsym to Support Phase 3 Dose Selection for Fezolinetant.

Jace C Nielsen, Jeffrey L Woodhead, Brett A Howell

|May 14, 2025
Quantitative Systems Toxicology Modeling of Acetaminophen Pharmacokinetics and Hepatic Biomarkers After Overdoses of Extended-Release and Immediate-Release Formulations in Adults With Chronic Alcohol Use or Low Glutathione.

Kyunghee Yang, James J Beaudoin, Brett A Howell

|Feb 03, 2025
Modeling and Simulation of Acetaminophen Pharmacokinetics and Hepatic Biomarkers After Overdoses of Extended-Release and Immediate-Release Formulations in Healthy Adults Using the Quantitative Systems Toxicology Software Platform DILIsym.

James J Beaudoin, Kyunghee Yang, Brett A Howell

|Dec 08, 2023
Quantitative Systems Toxicology Modeling Informed Safe Dose Selection of Emvododstat in Acute Myeloid Leukemia Patients.

Kyunghee Yang, Ronald Kong, Robert Spiegel

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Frequent Collaborators

3 joint publications

Kyunghee Yang

2 joint publications

James J Beaudoin

2 joint publications

Cathy K Gelotte

1 joint publications

Ronald Kong