David Scott

9PUBLICATIONS
82CO-AUTHORS
Molecular targetsBiologically active moleculesMedical molecular engineering of nucleic acids and proteinsNeural engineeringCheminformatics and quantitative structure-activity relationships
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Publications (9)

|Oct 23, 2026
RAF isoform selectivity of MEK inhibitors and rational design of a covalent ARAF-MEK inhibitor.

|Dec 03, 2024
Tilting the Scales toward EGFR Mutant Selectivity: Expanding the Scope of Bivalent "Type V" Kinase Inhibitors.

Florian Wittlinger, Surbhi P Chitnis, Calvin D Pham

|Jul 03, 2024
From hit to vial: Precision discovery and development of an imidazopyrimidine TLR7/8 agonist adjuvant formulation.

Dheeraj Soni, Francesco Borriello, David A Scott

|Mar 15, 2024
A Benzarone Derivative Inhibits EYA to Suppress Tumor Growth in SHH Medulloblastoma.

Grace H Hwang, Maria F Pazyra-Murphy, Hyuk-Soo Seo

|May 09, 2022
Molecular basis for cooperative binding and synergy of ATP-site and allosteric EGFR inhibitors.

Tyler S Beyett, Ciric To, David E Heppner

|Apr 29, 2022
A novel β-catenin/BCL9 complex inhibitor blocks oncogenic Wnt signaling and disrupts cholesterol homeostasis in colorectal cancer.

Helen Tanton, Tomasz Sewastianik, Hyuk-Soo Seo

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Frequent Collaborators

4 joint publications

Tyler S Beyett

3 joint publications

Michael J Eck

3 joint publications

David E Heppner

3 joint publications

Pasi A Jänne