Eric Therrien

5PUBLICATIONS
20CO-AUTHORS
Cheminformatics and quantitative structure-activity relationshipsBiomolecular modelling and designMolecular targetsBasic pharmacology
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Publications (5)

|Jun 17, 2026
Discovery of 2H-Pyrrolo[3,4‑c]pyridin-3-one Derivatives as Type-III c‑MET Inhibitors Enabled by Free-Energy Perturbation Calculations.

|Dec 13, 2024
In Silico Enabled Discovery of KAI-11101, a Preclinical DLK Inhibitor for the Treatment of Neurodegenerative Disease and Neuronal Injury.

H Rachel Lagiakos, Yefen Zou, Hideyuki Igawa

|Dec 12, 2024
Discovery of a Novel Mutant-Selective Epidermal Growth Factor Receptor Inhibitor Using an In Silico Enabled Drug Discovery Platform.

Hideyuki Igawa, Zef A Konst, Eric Therrien

|Sep 29, 2023
Identification of GDC-1971 (RLY-1971), a SHP2 Inhibitor Designed for the Treatment of Solid Tumors.

Alexander M Taylor, Bret R Williams, Fabrizio Giordanetto

|Jun 02, 2023
A Computational Physics-based Approach to Predict Unbound Brain-to-Plasma Partition Coefficient, Kp,uu.

Morgan Lawrenz, Mats Svensson, Mitsunori Kato

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Frequent Collaborators

2 joint publications

Aleksey I Gerasyuto

2 joint publications

Jeffrey A Bell

2 joint publications

Hideyuki Igawa

2 joint publications

Robert D Pelletier