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Jaroslav Roh

7PUBLICATIONS

18CO-AUTHORS

Gene and molecular therapyBiologically active moleculesCancer therapy (excl. chemotherapy and radiation therapy)Cheminformatics and quantitative structure-activity relationshipsMolecular targets

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Publications (7)

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|Oct 07, 2025

Scaffold Hopping in Tuberculosis Drug Discovery: Principles, Applications, and Case Studies.

Ondrej Kovar, Martin Kufa, Vladimir Finger

|Dec 29, 2023

Both Nitro Groups Are Essential for High Antitubercular Activity of 3,5-Dinitrobenzylsulfanyl Tetrazoles and 1,3,4-Oxadiazoles through the Deazaflavin-Dependent Nitroreductase Activation Pathway.

Galina Karabanovich, Viktória Fabiánová, Anthony Vocat

|Sep 23, 2021

Clinically Translatable Prevention of Anthracycline Cardiotoxicity by Dexrazoxane Is Mediated by Topoisomerase II Beta and Not Metal Chelation.

Eduard Jirkovský, Anna Jirkovská, Hana Bavlovič-Piskáčková

|Mar 22, 2021

Structure-Activity Relationship Study of Dexrazoxane Analogues Reveals ICRF-193 as the Most Potent Bisdioxopiperazine against Anthracycline Toxicity to Cardiomyocytes Due to Its Strong Topoisomerase IIβ Interactions.

Anna Jirkovská, Galina Karabanovich, Jan Kubeš

|Apr 08, 2020

Investigation of Structure-Activity Relationships of Dexrazoxane Analogs Reveals Topoisomerase II<i>β</i> Interaction as a Prerequisite for Effective Protection against Anthracycline Cardiotoxicity.

Petra Kollárová-Brázdová, Anna Jirkovská, Galina Karabanovich

|Aug 09, 2019

Development of 3,5-Dinitrophenyl-Containing 1,2,4-Triazoles and Their Trifluoromethyl Analogues as Highly Efficient Antitubercular Agents Inhibiting Decaprenylphosphoryl-β-d-ribofuranose 2'-Oxidase.

Galina Karabanovich, Jan Dušek, Karin Savková

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Frequent Collaborators

3 joint publications

Petra Štěrbová-Kovaříková

2 joint publications

Jan Korábečný

2 joint publications

Anna Jirkovská

2 joint publications

Galina Karabanovich

2 joint publications

Zuzana Pokorná

2 joint publications

Hana Bavlovič-Piskáčková

2 joint publications

Eduard Jirkovský

2 joint publications

Jan Kubeš

2 joint publications

Martin Štěrba

2 joint publications

Veronika Skalická

Frequent Collaborators

3 joint publications

Petra Štěrbová-Kovaříková

2 joint publications

Jan Korábečný

2 joint publications

Anna Jirkovská

2 joint publications

Galina Karabanovich

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