Brian Kuhlman

51PUBLICATIONS
123CO-AUTHORS
Deep learningBioinformatic methods developmentMolecular targetsReaction engineering (excl. nuclear reactions)Process control and simulation
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Publications (51)

|Jun 22, 2026
Deep learning based design of buried hydrogen bond networks with HBDesigner.

|May 04, 2026
De novo masking domains that gate TNF-family ligand assembly and activity.

|Mar 17, 2026
Enhancing Enzymatic Bioconjugation Efficiency via Computer-Based Installation of a Substrate Recruitment Domain.

Christopher Shelby, Kaylee P Kuzelka, Jonathan M Ellis

|Feb 23, 2026
Enhancing ML-based binder design with high-throughput screening: a comparison of mRNA and yeast display technologies.

Zhiyuan Yao, McGuire Metts, Avery K Huber

|Feb 20, 2026
De novo design of protein binders that target DELE1 to inhibit the mitochondrial stress response.

Rui Yang, Kaiyuan Zheng, McGuire Metts

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