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Update: influenza activity--United States, 1998-99 season

    Insights

    Influenza activity increased in the US starting mid-January 1999. Vaccine effectiveness against circulating influenza A(H3N2) viruses was estimated in a long-term-care facility outbreak investigation.

    Area of Science:

    • Public Health
    • Epidemiology
    • Virology

    Background:

    • Influenza surveillance data from October 4, 1998, through February 27, 1999, is summarized.
    • An influenza outbreak investigation was conducted in a long-term-care facility (LTCF).

    Purpose of the Study:

    • To summarize national influenza activity during the 1998-99 season.
    • To investigate an influenza outbreak in an LTCF.
    • To estimate 1998-99 influenza vaccine effectiveness against circulating influenza A(H3N2) viruses.

    Main Methods:

    • Analysis of national influenza surveillance data.
    • Outbreak investigation including case ascertainment and data collection within an LTCF.
    • Calculation of vaccine effectiveness using data from the LTCF.

    Main Results:

    • Influenza activity in the US began increasing in mid-January 1999.
    • Elevated influenza activity persisted in most US regions through February 27, 1999.
    • Influenza A(H3N2) viruses were circulating and vaccine effectiveness was estimated at the LTCF.

    Conclusions:

    • The 1998-99 influenza season saw a significant increase in activity starting mid-January.
    • LTCFs are vulnerable to influenza outbreaks, necessitating ongoing surveillance and vaccination efforts.
    • Vaccine effectiveness estimates provide crucial data for public health interventions during influenza seasons.

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