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Published on: November 21, 2017
Hypothermia with indoor occurrence is associated with a worse outcome
B Mégarbane1, O Axler, I Chary
1Department of Medical Intensive Care Unit and Medical Emergency, Antoine Béclère Hospital, Clamart, France. bruno-megarbane@wanadoo.fr
Insights
Patients admitted to the intensive care unit (ICU) for hypothermia face a higher mortality risk if found indoors. This study highlights indoor hypothermia as a significant predictor of poor outcomes, even with similar body temperatures.
Area of Science:
- Critical Care Medicine
- Environmental Health
- Toxicology
Background:
- Hypothermia, a dangerous drop in body temperature, affects numerous patients admitted to intensive care units (ICUs).
- Understanding the factors influencing hypothermia outcomes is crucial for improving patient care and survival rates.
Purpose of the Study:
- To characterize patients admitted to the ICU for hypothermia.
- To identify prognostic factors associated with hypothermia.
- To investigate whether the location where hypothermia occurred (indoors vs. outdoors) impacts patient outcomes.
Main Methods:
- A retrospective analysis of 81 consecutive ICU patients with a body temperature ≤35°C over 17 years.
- Patients were categorized based on whether hypothermia occurred indoors or outdoors.
- Prognostic factors were assessed using univariate and stepwise logistic regression analyses.
Main Results:
- The primary complications included acute renal failure (43%), aspiration pneumonia (22%), and rhabdomyolysis (22%).
- Indoor hypothermia patients (79%) had comorbidities like sepsis and neuropsychiatric disorders, unlike outdoor patients (21%) with intoxication.
- Illness severity (SAPS II ≥ 40) and indoor location independently predicted mortality.
Conclusions:
- Patients experiencing hypothermia indoors exhibit more severe illness and higher mortality rates compared to those found outdoors.
- The location of hypothermia occurrence is a critical prognostic indicator in the ICU setting.
Objective:
To describe patients admitted to intensive care unit (ICU) for hypothermia, evaluate prognostic factors, and test the hypothesis that patients found indoors have a worse outcome.
Design And Setting:
Retrospective clinical investigation in a medical ICU.
Patients:
Eighty-one consecutive patients admitted to ICU, with a body temperature of 35 degrees C or lower and rewarmed passively or with minimally invasive techniques, over a 17-year period.
Measurements And Results:
Patients were analyzed by age, gender, and causes of hypothermia and split into two groups (indoors and outdoors), according to the location where hypothermia occurred. Prognostic factors were determined by univariate method and stepwise logistic regression. The major complications were acute renal failure (43 %), aspiration pneumonia (22 %), rhabdomyolysis (22 %), and acute respiratory distress syndrome (12%). Principal comorbidities in the outdoor patients (21%) were alcohol and drug intoxication, and those in the indoor patients (79 %) were sepsis and neuropsychiatric disorders. Stepwise logistic regression identified two variables predictive of death: illness severity at admission (SAPS II > or = 40) and the location where hypothermia occurred (indoors versus outdoors).
Conclusions:
With equivalent body temperature, patients found indoors were more severely affected and died more frequently than those found outdoors.
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Homeostatic Imbalances in Body Temperature

