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Updated: Aug 24, 2026

Detecting the Lyme Disease Spirochete, Borrelia Burgdorferi, in Ticks Using Nested PCR
Published on: February 4, 2018
Insights
Lyme disease incidence rose 40% between 2001-2002. Public health efforts are crucial to reduce Borrelia burgdorferi infections in endemic areas.
Area of Science:
- Epidemiology
- Infectious Diseases
- Public Health
Background:
- Lyme disease (LD) is caused by Borrelia burgdorferi, transmitted by Ixodes ticks.
- LD became a nationally notifiable disease in 1991, with surveillance ongoing since 1982.
Purpose of the Study:
- To analyze reported Lyme disease cases from 2001-2002.
- To assess trends in LD incidence during this period.
Main Methods:
- Analysis of 40,792 Lyme disease cases reported to the CDC.
- Examination of national surveillance data for the years 2001 and 2002.
Main Results:
- A 40% increase in annual Lyme disease incidence was observed between 2001 and 2002.
- The data indicate a significant rise in LD cases during the study period.
Conclusions:
- The findings highlight the continued emergence of Lyme disease.
- Integrated pest management, landscaping, repellent use, and tick removal are essential for risk reduction in endemic areas.
Abstract:
Lyme disease (LD) is caused by the spirochete Borrelia burgdorferi and is transmitted through the bite of Ixodes spp. ticks. CDC began LD surveillance in 1982, and the Council of State and Territorial Epidemiologists designated LD a nationally notifiable disease in 1991. This report summarizes the analysis of 40,792 cases of LD reported to CDC during 2001-2002. The results of that analysis indicate that annual LD incidence increased 40% during this period. The continued emergence of LD underscores the need for persons in areas where LD is endemic to reduce their risk for infection through integrated pest management, landscaping practices, repellent use, and prompt removal of ticks.
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