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Updated: Aug 20, 2026

Label-Free Identification of Lymphocyte Subtypes Using Three-Dimensional Quantitative Phase Imaging and Machine Learning
Published on: November 19, 2018
[Bioptic typing and classification of Hodgkin's lymphomas--status in 1998]
1Ustav patologickej anatómie Jeseniovej LF Univerzity Komenského a MFN, Martin, Slovenská republika.
Insights
This review details the evolution of Hodgkin
Area of Science:
- Hematology
- Oncology
- Pathology
Context:
- Review of Hodgkin's lymphoma classification systems.
- Includes the Revised European-American Lymphoma (REAL) classification.
- Discusses the current World Health Organization (WHO) classification.
Purpose:
- To trace the development of Hodgkin's lymphoma classification.
- To describe morphological and immunohistochemical features.
- To provide differential diagnosis data.
Summary:
- Hodgkin's lymphomas are categorized into nodular lymphocyte-predominant and classical types.
- Morphological and immunohistochemical characteristics are detailed.
- Tumor biology, evolution, and differential diagnosis are covered.
Impact:
- Provides a comprehensive overview of Hodgkin's lymphoma classification.
- Aids in accurate diagnosis and understanding of tumor progression.
- Serves as a reference for pathologists and oncologists.
Abstract:
In the submitted review the authors give an account on the development of views regarding bioptic typing and classification of Hodgkin's lymphomas, incl. the REAL classification and the classification prepared at present by WHO. Hodgkin's lymphomas are divided into the nodular type with a predominance of lymphocytes--nodular paragranuloma and classical Hodgkin's lymphomas. In addition to a brief morphological description, the authors give also an account on immunohistochemical features of different types, short comments on the biology and evolution of tumourous diseases as well as basic data on the differential diagnosis of Hodgkin's lymphomas.

