Related Experiment Video

Updated: Aug 7, 2026

Use of In vivo Imaging to Monitor the Progression of Experimental Mouse Cytomegalovirus Infection in Neonates
05:53

Use of In vivo Imaging to Monitor the Progression of Experimental Mouse Cytomegalovirus Infection in Neonates

Published on: July 6, 2013

[Cytomegalovirus myelitis in immunocompetent adult]

N Ben Abdelhafidh1, R Battikh, J Laabidi

  • 1Service de médecine interne, hôpital militaire de Tunis, 1008 Mont-fleury Tunis, Tunisie.

La Revue De Medecine Interne
|June 27, 2006
PubMed

Insights

Cytomegalovirus (CMV) infection can cause acute myelitis in immunocompetent individuals, leading to neurological symptoms. Early diagnosis and ganciclovir treatment offer partial recovery, highlighting the importance of prompt intervention for CMV-associated myelitis.

Area of Science:

  • Neurology
  • Infectious Diseases

Background:

  • Cytomegalovirus (CMV) infection is highly prevalent, typically asymptomatic in immunocompetent individuals.
  • However, CMV can manifest as serious neurological syndromes, including encephalitis and myelitis.

Observation:

  • A case of a 64-year-old immunocompetent woman presented with acute limb weakness, paresthesias, and urinary retention.
  • Spinal MRI revealed enhancement from cervical to lumbar regions, consistent with myelitis.

Findings:

  • Diagnosis of CMV-associated myelitis was confirmed by positive CMV serology.
  • Treatment with ganciclovir resulted in partial improvement over five months.

Implications:

  • CMV acute myelitis in immunocompetent patients is rare, with pathogenesis likely immune-mediated.
  • Early diagnosis and treatment are crucial for improving prognosis in CMV myelitis.
Abstract

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