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Immediate adverse reactions to intravenous iodinated contrast media in computed tomography

Beatriz Cavalcanti Juchem1, Clarice Maria Dall'Agnol

  • 1Porto Alegre Hospital de Clínicas, Radiology Unit. bcjuchem@terra.com.br

Revista Latino-Americana De Enfermagem
|March 22, 2007
PubMed

Insights

Immediate adverse reactions to intravenous iodinated contrast media during computed tomography scans were mostly mild. Non-ionic contrast agents showed a lower reaction rate (1%) compared to ionic agents (12.5%).

Area of Science:

  • Radiology
  • Pharmacovigilance
  • Patient Safety

Background:

  • Intravenous iodinated contrast media are widely used in computed tomography (CT) scans.
  • Adverse reactions to contrast media can range from mild to severe.
  • Understanding local reaction rates is crucial for improving patient safety.

Purpose of the Study:

  • To investigate the incidence and characteristics of immediate adverse reactions to intravenous iodinated contrast media in hospitalized patients undergoing CT.
  • To compare reaction rates between ionic and non-ionic contrast agents.
  • To provide data for evaluating care delivery processes in a teaching hospital setting.

Main Methods:

  • Exploratory-descriptive, non-experimental quantitative research design.
  • Data collection on adverse reactions in hospitalized patients undergoing CT scans.
  • Analysis of reaction frequency, intensity, and type, including extravasation.

Main Results:

  • All reported adverse reactions were of mild intensity.
  • The frequency of adverse reactions was 12.5% for ionic contrast media and 1% for non-ionic contrast agents.
  • Extravasation occurred in 2.2% of peripheral vein injections without complications.

Conclusions:

  • Adverse reactions to iodinated contrast media in this cohort were predominantly mild.
  • Non-ionic contrast agents appear to have a lower adverse reaction profile.
  • Healthcare professionals should monitor and report local contrast media reaction rates to inform safety protocols.

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