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[Mycobacterium avium complex disease after conservative therapy for 3 years; report of a case]

E Matsuda1, K Okabe, T Yagi

  • 1Department of Chest Surgery, National Sanyo Hospital, Ube, Japan.

Kyobu Geka. the Japanese Journal of Thoracic Surgery
|August 14, 2008
PubMed

Insights

A 62-year-old woman with Mycobacterium avium complex lung disease underwent right upper lobectomy. Surgical treatment led to successful disease eradication with no recurrence observed 10 months post-operation.

Area of Science:

  • Pulmonology
  • Infectious Diseases
  • Thoracic Surgery

Background:

  • A 62-year-old female presented with an abnormal chest X-ray finding.
  • Initial imaging revealed a 2 cm cavitary nodule in the right upper lobe.

Observation:

  • Bronchofiberscopy confirmed Mycobacterium avium complex (MAC) infection.
  • The patient received 3 years of chemotherapy with slow, progressive lesion enlargement.

Findings:

  • Surgical intervention via right upper lobectomy was performed due to treatment failure.
  • Histopathological examination confirmed MAC infection in the resected lobe.

Implications:

  • Surgical resection can be an effective treatment option for refractory MAC lung disease.
  • This case highlights the importance of considering surgery for persistent or progressive MAC infections unresponsive to chemotherapy.

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