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Primary cardiac lymphoma presenting with cardiac tamponade
Lee Fong Ling1, Ping Chai, Adrian C L Kee
1Cardiac Department, National University Hospital, Singapore. leefong7@yahoo.com.sg
Insights
Primary cardiac lymphoma (PCL) is rare, even in immunocompetent individuals. Early diagnosis requires a high index of suspicion and imaging like echocardiography.
Area of Science:
- Cardiology
- Oncology
- Diagnostic Imaging
Background:
- Primary cardiac lymphoma (PCL) is an exceedingly rare malignancy.
- PCL typically affects immunocompromised patients but can occur in immunocompetent individuals.
- Diagnostic challenges arise due to PCL's varied presentations and subtle early clinical signs.
Observation:
- A case of PCL in a 55-year-old immunocompetent male is presented.
- Initial symptoms included pyrexia of unknown origin, chest pain, and dyspnea.
- Cardiac tamponade and a significant cardiac mass were identified via echocardiography and cardiovascular magnetic resonance imaging.
Findings:
- PCL can manifest atypically in immunocompetent patients.
- Echocardiography and cardiovascular magnetic resonance are crucial for detecting cardiac masses.
- A high index of suspicion is essential for timely PCL diagnosis.
Implications:
- This case highlights the importance of considering PCL in immunocompetent patients with unexplained cardiac symptoms.
- Advanced imaging modalities play a vital role in diagnosing rare cardiac conditions.
- Increased physician awareness can improve early detection and management of primary cardiac lymphoma.
Abstract:
Primary cardiac lymphoma (PCL) is rare and occurs more commonly in immunocompromised patients. It can present in various ways, and diagnosis is particularly challenging, especially for the unsuspecting physician. We report a case of PCL in an immunocompetent 55-year-old man who initially presented with pyrexia of unknown origin, chest pain, dyspnea, and few early clinical signs, but who was later found to have cardiac tamponade and a large cardiac mass on echocardiography and cardiovascular magnetic resonance. A high index of suspicion is needed to diagnose PCL, and echocardiogram remains an important diagnostic tool.
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