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Analysis of 18FDG PET/CT Imaging as a Tool for Studying Mycobacterium tuberculosis Infection and Treatment in Non-human Primates
Published on: September 5, 2017
Diffuse infiltrative cardiac tuberculosis
Gurpreet S Gulati1, Shyam S Kothari
1Department of Cardiac Radiology, All India Institute of Medical Sciences, New Delhi - 110 029, India.
Insights
This study showcases cardiac magnetic resonance imaging findings of a rare cardiac tuberculosis presentation. The unusual nodular masses infiltrating the heart showed significant improvement with tuberculosis treatment.
Area of Science:
- Cardiology
- Infectious Diseases
- Radiology
Background:
- Cardiac tuberculosis is a rare manifestation of Mycobacterium tuberculosis infection.
- It can present with diverse imaging findings, often mimicking other cardiac pathologies.
- Early diagnosis and treatment are crucial for patient outcomes.
Purpose of the Study:
- To describe the characteristic cardiac magnetic resonance imaging (CMR) findings of an unusual form of cardiac tuberculosis.
- To illustrate the potential for significant lesion resolution following antitubercular therapy.
Main Methods:
- Case presentation of a patient with cardiac tuberculosis.
- Detailed analysis of cardiac magnetic resonance imaging (CMR) features.
- Correlation of imaging findings with clinical response to antitubercular therapy.
Main Results:
- Cardiac magnetic resonance imaging revealed nodular masses in a sheet-like distribution.
- These lesions infiltrated the outer myocardium and pericardium across multiple cardiac chambers.
- Significant resolution of the cardiac lesions was observed after initiating antitubercular therapy.
Conclusions:
- Cardiac tuberculosis can present with distinctive, albeit unusual, imaging patterns on CMR.
- CMR is valuable in diagnosing and monitoring cardiac tuberculosis.
- Antitubercular therapy can lead to substantial improvement in cardiac manifestations of tuberculosis.
Abstract:
We present the cardiac magnetic resonance images of an unusual form of cardiac tuberculosis. Nodular masses in a sheet-like distribution were seen to infiltrate the outer myocardium and pericardium along most of the cardiac chambers. The lesions showed significant resolution on antitubercular therapy.
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