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Reactive lymphoid hyperplasia of lacrimal canaliculus caused by a silicone plug
Jae Hyung Han1, Ju Wan Park, Sung Chul Kim
1Department of Ophthalmology and Visual Science, Yeouido St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea.
Insights
Lacrimal silicone plugs can cause rare complications like granulomas. A case study highlights reactive lymphoid hyperplasia mimicking lymphoma after plug insertion, emphasizing the need for accurate diagnosis.
Area of Science:
- Ophthalmology
- Pathology
Background:
- Lacrimal silicone plugs are used for treating epiphora.
- Complications are rare, with granuloma being the most common.
Observation:
- A 57-year-old woman presented with lower eyelid swelling and a mass from the lower punctum.
- The patient had previously undergone lacrimal silicone plug insertion.
Findings:
- Surgical resection revealed lymphoid hyperplasia.
- Immunophenotypic markers (CD3, CD20, BCL2) confirmed reactive lymphoid hyperplasia.
- This condition can be mistaken for lymphoma on initial histopathology.
Implications:
- Accurate histopathological diagnosis is crucial to differentiate reactive lymphoid hyperplasia from malignancy.
- Understanding this complication aids in patient management and diagnosis.
Abstract:
Complications of tumorigenesis by a lacrimal silicone plug are rarely reported and most of them were cases of granuloma due to chronic inflammation. The authors present a case of a 57-year-old healthy woman complaining of lower eyelid swelling and protruding mass from lower punctum who had undergone insertion of a lacrimal silicone plug. Surgical mass resection was performed and initial histopathology revealed lymphoid hyperplasia. Additional immunophenotypic markers CD3, CD20, and BCL2 showed reactive lymphoid hyperplasia. It has a histopathologic significance in that it can mimic lymphoma and should be distinguished from malignancy.
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