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Published on: December 23, 2016
Parotid disease associated with human immunodeficiency virus infection
1Department of Otolaryngology-Head and Neck Surgery, New York Medical College, NY.
Insights
Cystic parotid enlargement is a new sign of human immunodeficiency virus (HIV) infection, often appearing early in the illness. Diagnosis typically involves HIV testing and CT scans, with further tests sometimes needed.
Area of Science:
- Infectious Diseases
- Oncology
- Radiology
Background:
- Cystic parotid enlargement is an emerging clinical finding.
- This condition is associated with human immunodeficiency virus (HIV) infection.
- It may be linked to Lymphadenopathy Syndrome (LAS).
Purpose of the Study:
- To describe cystic parotid enlargement as a manifestation of HIV.
- To highlight its early occurrence in HIV-related illnesses.
- To outline diagnostic approaches.
Main Methods:
- Literature review of HIV-related parotid conditions.
- Analysis of clinical presentations.
- Review of diagnostic imaging and pathology.
Main Results:
- Cystic parotid enlargement is a recognized manifestation of HIV.
- It often presents early in the HIV disease spectrum.
- Serologic tests for HIV and CT imaging are key diagnostic tools.
Conclusions:
- Cystic parotid enlargement signifies HIV infection.
- Early diagnosis is facilitated by serology and CT.
- Cytology or histology may be necessary for definitive diagnosis and treatment planning.
Abstract:
Cystic parotid enlargement is a newly recognized manifestation of HIV infection. It commonly occurs early in the spectrum of HIV-related illnesses and may be part of LAS. Serologic confirmation of HIV infection and CT imaging usually establishes the diagnosis. Cytologic or histopathologic evaluation may be required for diagnostic confirmation and for management.
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