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Intraocular Lymphoma Masquerading as Recurrent Iridocyclitis: Findings Based on in vivo Confocal Microscopy
Pu Zhang1, Jiao Tian1, Ling Gao1
1a Department of Ophthalmology, The Second Xiangya Hospital , Central South University , Changsha , Hunan , P.R. China.
Insights
In vivo confocal microscopy (IVCM) aids in differentiating intraocular inflammation from neoplastic diseases. This technique showed complete remission of intraocular lymphoma after treatment.
Area of Science:
- Ophthalmology
- Medical Imaging
Background:
- Distinguishing intraocular inflammatory and neoplastic diseases can be challenging.
- In vivo confocal microscopy (IVCM) offers high-resolution imaging of ocular tissues.
Observation:
- A case of neoplastic masquerade syndrome was evaluated.
- Initial IVCM examination was performed on the patient.
Findings:
- IVCM revealed a complete remission of intraocular lymphoma following six intravitreal methotrexate injections.
- The patient initially presented with neoplastic masquerade syndrome.
Implications:
- IVCM findings can provide valuable indications for differentiating intraocular inflammatory conditions from neoplasms.
- While not definitive for diagnosing intraocular neoplasm, IVCM supports clinical assessment.
Purpose:
To emphasize the application prospects of in vivo confocal microscopy (IVCM) in distinguishing intraocular lesions from inflammatory and neoplastic diseases.
Methods:
Retrospective case report.
Results:
A patient with neoplastic masquerade syndrome initially underwent IVCM examination. After six separate intravitreal injections of 400 mg/0.1 ml methotrexate, IVCM revealed a complete remission of intraocular lymphoma.
Conclusions:
Although IVCM findings alone are not enough to diagnose intraocular neoplasm with absolute certainty, they can provide useful indication for distinguishing between intraocular inflammatory diseases and neoplasms.
