On-site cytological diagnosis of cylindroma: A case report

Area of Science:

• Dermatopathology
• Surgical Pathology
• Cytopathology

Background:

• Skin adnexal tumors are a diverse group of neoplasms originating from hair follicles, sebaceous glands, or sweat glands.
• Cylindromas, a subtype of adnexal tumors, are typically benign but can rarely be malignant.
• Accurate and timely diagnosis is crucial for appropriate patient management.

Observation:

• A 70-year-old female presented with a 6-month history of right auricle swelling.
• Cytology revealed small, round to oval cells with hyperchromatic nuclei and scant cytoplasm.
• The background showed basement membrane-like material, suggestive of cylindroma.

Findings:

• Rapid onsite staining and routine cytology led to a preliminary diagnosis of skin adnexal tumor, likely cylindroma.
• Excisional biopsy confirmed the diagnosis of cylindroma.
• The tumor was located in the subcutaneous tissue.

Implications:

• Rapid onsite staining and cytology are valuable tools for diagnosing rare subcutaneous tumors like cylindroma.
• This diagnostic approach can be particularly useful in the absence of primary salivary gland tumors.
• Early and accurate cytological diagnosis facilitates prompt surgical intervention and management.