Related Experiment Video

Updated: Nov 15, 2025

Analysis of 18FDG PET/CT Imaging as a Tool for Studying Mycobacterium tuberculosis Infection and Treatment in Non-human Primates
10:04

Analysis of 18FDG PET/CT Imaging as a Tool for Studying Mycobacterium tuberculosis Infection and Treatment in Non-human Primates

Published on: September 5, 2017

19.0K

COVID-19 Vaccine-Related Local FDG Uptake

Mohan Doss1, Shazia K Nakhoda2, Yi Li1

  • 1From the Nuclear Medicine and PET Service, Department of Diagnostic Imaging.

Clinical Nuclear Medicine
|March 4, 2021
PubMed

Insights

Increased FDG uptake in lymph nodes after COVID-19 vaccination is a potential finding. This case highlights the importance of considering recent vaccination when interpreting PET/CT scans in lymphoma patients.

Area of Science:

  • Oncology
  • Immunology
  • Radiology

Background:

  • Positron Emission Tomography/Computed Tomography (PET/CT) is crucial for cancer staging and monitoring.
  • COVID-19 vaccination is widespread and can elicit immune responses.

Observation:

  • A 70-year-old female with relapsed Hodgkin lymphoma underwent PET/CT scan.
  • The scan revealed increased fluorodeoxyglucose (FDG) uptake in the left deltoid muscle and left axillary lymph nodes.
  • The patient had received the Pfizer-BioNTech COVID-19 vaccine two days prior.

Findings:

  • The observed increased FDG uptake in lymph nodes is consistent with an immune response to the COVID-19 vaccine.
  • This finding mimics potential disease recurrence or metastasis in lymphoma patients.

Implications:

  • Radiologists and oncologists must be aware of post-vaccination imaging changes.
  • Considering vaccination status can prevent misinterpretation of PET/CT scans, avoiding unnecessary interventions.

More Related Videos

Gene Regulation and Targeted Therapy in Gastric Cancer Peritoneal Metastasis: Radiological Findings from Dual Energy CT and PET/CT10:28

Gene Regulation and Targeted Therapy in Gastric Cancer Peritoneal Metastasis: Radiological Findings from Dual Energy CT and PET/CT

Published on: January 22, 2018

11.3K
Automated Preparation of [68Ga]Ga-3BP-3940 on a Synthesis Module for PET Imaging of the Tumor Microenvironment10:33

Automated Preparation of [68Ga]Ga-3BP-3940 on a Synthesis Module for PET Imaging of the Tumor Microenvironment

Published on: April 25, 2025

722

Related Concept Videos

Positron Emission Tomography01:29

Positron Emission Tomography

Positron emission tomography (PET) is a medical imaging technique involving radiopharmaceuticals — substances that emit short-lived radiation. Although the first PET scanner was introduced in 1961, it took 15 more years before radiopharmaceuticals were combined with the technique and revolutionized its potential.
One of the main requirements of a PET scan is a positron-emitting radioisotope, which is produced in a cyclotron and then attached to a substance used by the part of the body...
6.5K
Radiological Investigation III: Pulmonary Angiogram and PET Scan01:13

Radiological Investigation III: Pulmonary Angiogram and PET Scan

Radiological investigations are paramount in the diagnosis and management of various pulmonary diseases. Two essential investigations are the Pulmonary Angiogram and the Positron Emission Tomography (PET) Scan.
Pulmonary Angiogram
A Pulmonary Angiogram is an invasive procedure involving injecting a contrast medium through a catheter threaded into the pulmonary artery or the right side of the heart to visualize the pulmonary vasculature. Computed Tomography (CT) scans have mainly replaced this...
252