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Method for Efficient Refolding and Purification of Chemoreceptor Ligand Binding Domain
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Selección de proteínas plegadas de una biblioteca de elementos estructurales secundarios.

James J Graziano1, Wenshe Liu, Roshan Perera

  • 1Department of Chemistry and the Skaggs Institute for Chemical Biology, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, California 92037, USA.

Journal of the American Chemical Society
|December 11, 2007
PubMed
Resumen

Los investigadores desarrollaron una nueva estrategia de evolución de proteínas para crear nuevos polipéptidos. Este método generó con éxito proteínas solubles con estructuras secundarias definidas, algunas sin homología conocida.

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