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Salud Pública

Muhammad Safiullah1, Muhammad Atif Bashir1, Muhammad Ali1

  • 1King Edward Medical University, Lahore, Punjab, Pakistan.

Alzheimer's & dementia : the journal of the Alzheimer's Association
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Resumen
Este resumen es generado por máquina.

La carga de la enfermedad de Alzheimer y otras demencias (EAOD) en Pakistán es alta, con una mortalidad creciente a pesar de una incidencia decreciente. El envejecimiento de la población y los riesgos metabólicos como la glucosa plasmática en ayunas alta son factores clave, que afectan particularmente a las mujeres mayores.

Palabras clave:
Enfermedad de AlzheimerDemenciaPakistánSalud PúblicaEnvejecimiento de la PoblaciónRiesgos MetabólicosGlucosa Plasmática en Ayunas

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Área de la Ciencia:

  • Neurology; Public Health; Geriatrics

Sus antecedentes:

  • Alzheimer's disease and other dementias (ADOD) pose a significant health challenge globally and in Pakistan.; Understanding the burden and trends of ADOD is crucial for public health planning.

Objetivo del estudio:

  • To examine the national and provincial burden of Alzheimer's disease and other dementias (ADOD) in Pakistan.; To identify attributable factors and temporal trends of ADOD from 1990 to 2021.

Principales métodos:

  • Utilized the Global Burden of Diseases Study 2021 data for Pakistan.; Estimated incidence, mortality rates, and disability-adjusted life years (DALYs) for ADOD.; Analyzed temporal trends using average annual percentage changes (AAPCs).

Principales resultados:

  • Pakistan has the highest ADOD burden in South Asia after Bhutan.; Age-standardized incidence rates (ASIR) decreased, while death rates (ASDR) and DALYs rates increased from 1990-2021.; Population aging drove increases in ADOD cases and DALYs; older females and Islamabad region showed higher burdens. High fasting plasma glucose was a leading mortality cause.

Conclusiones:

  • ADOD is a major concern requiring targeted healthcare interventions, especially for older women.; Prioritizing prevention strategies for metabolic risks like high fasting plasma glucose is essential to reduce ADOD mortality.