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Updated: Jul 28, 2026

Characterization of G Protein-coupled Receptors by a Fluorescence-based Calcium Mobilization Assay
11:49

Characterization of G Protein-coupled Receptors by a Fluorescence-based Calcium Mobilization Assay

Published on: July 28, 2014

Caracterización de un receptor multicomponente para el GDNF

J J Treanor1, L Goodman, F de Sauvage

  • 1Department of Neuroscience, Genentech, Inc., South San Francisco, California 94080, USA.

Nature
|July 4, 1996
PubMed
Resumen

El factor neurotrófico derivado de la línea celular glial (GDNF) requiere una nueva proteína, GDNFR-alfa, para sus efectos. Esta proteína forma un complejo con el receptor Ret, iniciando vías de señalización cruciales para la supervivencia y el desarrollo neuronal.

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