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Updated: May 12, 2026

Immunostaining for DNA Modifications: Computational Analysis of Confocal Images
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Immunostaining for DNA Modifications: Computational Analysis of Confocal Images

Published on: September 7, 2017

CTCFは,H19/Igf2ロカスにおけるメチレーションに敏感な増強剤阻害活性を媒介する

A T Hark1, C J Schoenherr, D J Katz

  • 1Howard Hughes Medical Institute and Department of Molecular Biology, Princeton University, New Jersey 08544, USA.

Nature
|June 6, 2000
PubMed
まとめ

H19の近くのインプリント制御領域は境界線として作用し,遺伝子相互作用をブロックします. この領域へのCTCF結合は,遺伝子の静止を防ぐが,メチル化はこの境界関数を破壊する.

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