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Updated: Feb 8, 2026

GPI Anchoring of Proteins in the ER Membrane
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GPI Anchoring of Proteins in the ER Membrane

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RNAベースの進化の古さについて

Gerald F Joyce1

  • 1Department of Chemistry and The Skaggs Institute for Chemical Biology, The Scripps Research Institute, La Jolla, CA 92037, USA. gjoyce@scripps.edu

Nature
|July 12, 2002
PubMed
まとめ

現代の生命はDNAとタンパク質を用いるが,証拠は,もっと昔の"RNA世界"があったことを示唆している. この原始的な段階では,リボ核酸 (RNA) 分子は遺伝情報を保存し,反応を触媒化し,現在の生命形態を先行した.

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GPI-anchoring is a post-translational, reversible protein modification that is ubiquitous in eukaryotes. Such proteins are primarily present on the exoplasmic leaflet of the plasma membrane.
GPI-anchor structure
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