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設計された螺旋ペプチドは,膜内プロテアゼを阻害する

Chittaranjan Das1, Oksana Berezovska, Thekla S Diehl

  • 1Center for Neurologic Diseases, Harvard Medical School, Boston, Massachusetts 02115, USA.

Journal of the American Chemical Society
|September 25, 2003
PubMed
まとめ

短い螺旋状ペプチドは,基板結合を阻害することによってガンマ分泌酵素を阻害し,アルツハイマー病の新たな治療戦略を提供します. D-アミノ酸ペプチドが最も有望であることが示されています.

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