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Updated: Jul 13, 2026

Formation of Ordered Biomolecular Structures by the Self-assembly of Short Peptides
07:26

Formation of Ordered Biomolecular Structures by the Self-assembly of Short Peptides

Published on: November 21, 2013

ベータプロリンオリゴマーの構成的行動

Leah M Sandvoss1, Heather A Carlson

  • 1Department of Medicinal Chemistry, College of Pharmacy, 428 Church St., Ann Arbor, Michigan 48109-1065, USA.

Journal of the American Chemical Society
|December 18, 2003
PubMed
まとめ

ベータプロリン (ピロリジン-3-カルボキシル酸) の形状を計算した. ベータプロリンヘリクは,アルファプロリンヘリクと比較して逆のハンドル性を示し,タンパク質を模倣するアプリケーションの可能性を秘めている.

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Protein Organization01:13

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Protein Folding01:22

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Protein and Protein Structure02:15

Protein and Protein Structure

Proteins are one of the most abundant organic molecules in living systems and have the most diverse range of functions of all macromolecules. Proteins may be structural, regulatory, contractile, or protective. They may serve in transport, storage, or membranes; or they may be toxins or enzymes. Their structures, like their functions, vary greatly. They are all, however, amino acid polymers arranged in a linear sequence.
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Protein Folding01:22

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Protein Organization01:24

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Proteins are polymers of amino acid residues. They are versatile and responsible for different cellular functions, including DNA replication, molecular transport, catalysis, and structural support. Proteins have a hierarchical structure comprising at least three levels of organization: primary, secondary, and tertiary structure. Some large proteins have a quaternary structure where individual protein subunits are linked together.
The primary structure of a protein is its amino acid sequence.
Protein Folding01:25

Protein Folding

Proteins are chains of amino acids linked together by peptide bonds. Upon synthesis, a protein folds into a three-dimensional conformation, critical to its biological function. Interactions between its constituent amino acids guide protein folding, and hence the protein structure is primarily dependent on its amino acid sequence.
Protein Structure Is Critical to Its Biological Function
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