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人間のDicerとバクテリアのRNase IIIのための単一の処理センターモデル

Haidi Zhang1, Fabrice A Kolb, Lukasz Jaskiewicz

  • 1Friedrich Miescher Institute for Biomedical Research, PO Box 2543, 4002 Basel, Switzerland.

Cell
|July 10, 2004
PubMed
まとめ

Human DicerおよびE. coliのRNase III酵素は,RNA処理のための単一の触媒センターを利用し,特定の2 nt 3'オーバーハングを生成します. これは,DicerがRNase IIIドメインの分子内二分化によって機能することを示唆しています.

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Bacteria and archaea are susceptible to viral infections just like eukaryotes; therefore, they have developed a unique adaptive immune system to protect themselves. Clustered regularly interspaced short palindromic repeats and CRISPR-associated proteins (CRISPR-Cas) are present in more than 45% of known bacteria and 90% of known archaea.
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