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Updated: May 3, 2026

Isolation of Ribosome Bound Nascent Polypeptides in vitro to Identify Translational Pause Sites Along mRNA
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シングルRNAポリメラーゼ分子による停止のシーケンス解析検出

Kristina M Herbert1, Arthur La Porta, Becky J Wong

  • 1Biophysics Program, Stanford University, CA 94305, USA.

Cell
|June 17, 2006
PubMed
まとめ

RNAポリメラーゼ (RNAP) の停止は,遺伝子調節に不可欠である. この研究は,これまでほとんど理解されていなかった,至る所に存在するパウスが,シーケンス固有であり,規制的なパウスサイトと関連しており,RNAPの転写ダイナミクスを明らかにすることを明らかにしています.

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