,DNA.

Anja Groth1, Walter Rocha, Alain Verreault

  • 1Laboratory of Nuclear Dynamics and Genome Plasticity, UMR 218 CNRS/Institut Curie, 26 rue d'Ulm, 75248 Paris, Cedex 5, France.

Cell
|February 27, 2007
PubMed
まとめ

DNAの配列とクロマチンの組織を維持することは,真核生物にとって極めて重要です. 細胞は,DNA複製と修復の間に表遺伝子情報の忠実な継承を確保するために,核細胞組成とクロマチンの成熟経路を利用します.

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The DNA Replication Fork01:02

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Duplication of Chromatin Structure02:05

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The DNA Replication Fork

An organism’s genome needs to be duplicated in an efficient and error-free manner for its growth and survival. The replication fork is a Y-shaped active region where two strands of DNA are separated and replicated continuously. The coupling of DNA unzipping and complementary strand synthesis is a characteristic feature of a replication fork.   Organisms with small circular DNA, such as E. coli, often have a single origin of replication; therefore, they have only two replication forks, one in...
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