関連する実験動画

Updated: Jul 13, 2026

Single-Molecule Fluorescence Visualization of DNA Polymerase Dynamics at G-Quadruplexes
05:37

Single-Molecule Fluorescence Visualization of DNA Polymerase Dynamics at G-Quadruplexes

Published on: April 4, 2025

ヒトのテロメアDNAは,分子混雑の条件下でK+溶液で並列鎖の分子内G四重複を形成する

Yong Xue1, Zhong-yuan Kan, Quan Wang

  • 1Laboratory of Biochemistry and Biophysics, College of Life Sciences, Wuhan University, Wuhan 430072, P. R. China.

Journal of the American Chemical Society
|August 21, 2007
PubMed
まとめ

人間のテロメアDNAは,混雑した細胞環境で安定した平行鎖のG-四重複構造を形成し,テロメラーゼ活性に影響を与えます. この発見は,G-quadruplex構造を標的としたがん治療薬の開発において極めて重要です.

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Single-molecule Manipulation of G-quadruplexes by Magnetic Tweezers

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