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Updated: Jan 20, 2026

Correlating Gene-specific DNA Methylation Changes with Expression and Transcriptional Activity of Astrocytic KCNJ10 Kir4.1
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Correlating Gene-specific DNA Methylation Changes with Expression and Transcriptional Activity of Astrocytic KCNJ10 Kir4.1

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精密な発達遺伝子発現は,世界的にストキャスティックな転写活動から生じる

Shawn C Little1, Mikhail Tikhonov2,3, Thomas Gregor2,3

  • 1Department of Molecular Biology, Howard Hughes Medical Institute, Princeton University, Princeton, NJ 08544, USA.

Cell
|August 20, 2013
PubMed
まとめ

発達の精度は,遺伝子発現ノイズの平均から生まれる. 高い転写変動 (~45%) があるにもかかわらず,mRNAレベルはドロソフィラ胚の核の間では ~8%しか変化せず,正確なパターンを確保します.

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Using an Automated Cell Counter to Simplify Gene Expression Studies: siRNA Knockdown of IL-4 Dependent Gene Expression in Namalwa Cells10:34

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