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Updated: Jan 24, 2026

Assays for the Degradation of Misfolded Proteins in Cells
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ミトコンドリアタンパク質の転位に関連する分解

Christoph U Mårtensson1,2, Chantal Priesnitz1,2, Jiyao Song1

  • 1Institute of Biochemistry and Molecular Biology, ZBMZ, Faculty of Medicine, University of Freiburg, Freiburg, Germany.

Nature
|May 24, 2019
PubMed
まとめ

研究者達はミトコンドリアの タンパク質輸入チャネルを塞ぐ 新しい品質管理経路を発見しました この経路はミトコンドリアのタンパク質転移関連分解 (mitoTAD) と呼ばれ,Ubx2とCdc48を使って 閉じ込められたタンパク質を除去し,ミトコンドリアの機能を維持します.

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