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Urinary Bladder01:23

Urinary Bladder

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The urinary bladder is a hollow, muscular sac that temporarily stores urine before it is expelled from the body. It can hold approximately 600 mL of urine prior to micturition. The bladder is retroperitoneal and located behind the pubic symphysis in the pelvic floor.
In males, the bladder is situated in front of the rectum, while in females, it is positioned anterior to the vagina and uterus. The bladder floor contains an inverted triangular area called the trigone, defined by the two ureteric...
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Imaging Studies VI: Voiding Cystourethrography and Cystography01:22

Imaging Studies VI: Voiding Cystourethrography and Cystography

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Voiding Cystourethrography (VCUG) and Cystography are specialized radiographic procedures used to examine the structure and function of the bladder and urethra.Voiding Cystourethrography (VCUG)A Voiding Cystourethrogram (VCUG) is a diagnostic imaging procedure that assesses the anatomy and function of the lower urinary tract. It focuses on the bladder, bladder neck, and urethra, helping detect abnormalities such as vesicoureteral reflux (VUR)—the backward or reverse flow of urine into the...
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Anatomy of the Genitourinary System II: Bladder and Urethra01:19

Anatomy of the Genitourinary System II: Bladder and Urethra

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The lower urinary system consists of the urinary bladder and urethra, which are essential in storing and expelling urine from the body. Together with the internal and external sphincters, these structures work together to regulate urination effectively.Anatomy of the BladderThe urinary bladder is a muscular, stretchable organ behind the pubic bone and in front of the rectum. In females, the bladder is positioned anterior to the vagina and inferior to the uterus, while in males, it is located...
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Urinary Tract Calculi II: Pathophysiology and Clinical Manifestations01:26

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Renal calculi, commonly termed kidney stones, are crystalline solid masses that form in the kidneys but can occur at any point within the urinary system, encompassing the kidneys, ureters, bladder, and urethra.The pathophysiology of renal stones involves several key factors: supersaturation of the urine with stone-forming constituents, changes in urine pH, a decrease in urine volume, and the presence of substances that promote or inhibit stone formation.Supersaturation of Urine: This is the...
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An Orthotopic Bladder Cancer Model for Gene Delivery Studies
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膀 がん: 概要

Andrew T Lenis1, Patrick M Lec1, Karim Chamie

  • 1Institute of Urologic Oncology (IUO), Department of Urology, David Geffen School of Medicine, University of California, Los Angeles.

JAMA
|November 17, 2020
PubMed
まとめ
この要約は機械生成です。

膀がんの診断と治療は 大きく進歩しました 免疫療法や標的薬を含む新しい治療法は,筋肉侵襲性および進行性の膀がんに対して,BCGのような従来の治療法を超えて拡張された選択肢を提供します.

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科学分野:

  • 腫瘍学
  • 泌尿器科

背景:

  • 膀癌は非侵襲的な形態から攻撃的な形態のスペクトルを持つ一般的な悪性腫瘍です.
  • 危険因子 に は 年齢,男性 性,喫煙 など が 含まれる.
  • 腫瘍に血液が流れており, 膀鏡検査と画像検査が必要である.

研究 の 目的:

  • 膀がんの診断と治療の状況を見直す
  • 筋肉を侵攻しない 筋肉を侵攻する 進行した膀がんの治療の進歩を強調する

主な方法:

  • 強化されたシストスコピーを含む現在の診断方法のレビュー.
  • 膀がんの異なる段階における治療戦略の検討
  • 免疫療法や標的薬などの新興治療法の探索

主要な成果:

  • カルメッテ・ゲーリン (BCG) の腸内細菌は,中間/高リスクの非筋肉侵襲性膀がんの標準である.
  • 強化されたシストスコピーは腫瘍の検出を改善し,再発を減らすことができます.
  • 筋肉侵襲性および進行した疾患の治療は著しく拡大しました.

結論:

  • 分子と遺伝子の洞察が 膀がんの診断と治療に変化をもたらしています
  • 免疫療法,標的治療,および抗体-薬剤結合剤は,進行した疾患において極めて重要です.
  • 膀がんの治療法は 拡大され続けており 患者の治療も改善されています