Jove
Visualize
お問い合わせ

関連する概念動画

Noncovalent Attractions in Biomolecules02:35

Noncovalent Attractions in Biomolecules

52.7K
Noncovalent attractions are associations within and between molecules that influence the shape and structural stability of complexes. These interactions differ from covalent bonding in that they do not involve sharing of electrons.
Four types of noncovalent interactions are hydrogen bonds, van der Waals forces, ionic bonds, and hydrophobic interactions.
Hydrogen bonding results from the electrostatic attraction of a hydrogen atom covalently bonded to a strong-electronegative atom like oxygen,...
52.7K
Cooperative Binding of Transcription Regulators02:13

Cooperative Binding of Transcription Regulators

6.5K
Transcriptional regulators bind to specific cis-regulatory sequences in the DNA to regulate gene transcription. These cis-regulatory sequences are very short, usually less than ten nucleotide pairs in length. The short length means that there is a high probability of the exact same sequence randomly occurring throughout the genome.  Since regulators can also bind to groups of similar sequences, this further increases the chances of random binding. Transcriptional regulators form...
6.5K
Cooperative Allosteric Transitions01:58

Cooperative Allosteric Transitions

8.0K
Cooperative allosteric transitions can occur in multimeric proteins, where each subunit of the protein has its own ligand-binding site. When a ligand binds to any of these subunits, it triggers a conformational change that affects the binding sites in the other subunits; this can change the affinity of the other sites for their respective ligands. The ability of the protein to change the shape of its binding site is attributed to the presence of a mix of flexible and stable segments in the...
8.0K
Protein-protein Interfaces02:04

Protein-protein Interfaces

12.7K
Many proteins form complexes to carry out their functions, making protein-protein interactions (PPIs) essential for an organism's survival. Most PPIs are stabilized by numerous weak noncovalent chemical forces. The physical shape of the interfaces determines the way two proteins interact. Many globular proteins have closely-matching shapes on their surfaces, which form a large number of weak bonds. Additionally, many PPIs occur between two helices or between a surface cleft and a...
12.7K
Van der Waals Interactions01:24

Van der Waals Interactions

65.2K
Atoms and molecules interact with each other through intermolecular forces. These electrostatic forces arise from attractive or repulsive interactions between particles with permanent, partial, or temporary charges. The intermolecular forces between neutral atoms and molecules are ion–dipole, dipole–dipole, and dispersion forces, collectively known as van der Waals forces.
65.2K
Molecular Geometry and Dipole Moments02:36

Molecular Geometry and Dipole Moments

13.7K
The VSEPR theory can be used to determine the electron pair geometries and molecular structures as follows:
13.7K

こちらも読む

関連記事

共著者、ジャーナル、引用グラフによってこの研究に関連する記事。

並び替え
Same author

Cucurbituril-based anion-conducting membranes with supramolecular nanopores.

Nature·2026
Same author

Site-Specifically Modified Circular Ribonucleic Acid Serves as Multitarget miRNA Sponge with Low Immunogenicity.

Journal of the American Chemical Society·2026
Same author

Effects of high temperature with pressure post-treatment on the Vickers hardness, color stability, and translucency of 3D-printed denture teeth resin under thermocycling conditions.

BMC oral health·2026
Same author

Hypoxia-Responsive Thio-Perylene Diimides Delivered via pH-Responsive Polypeptide Nanoparticles: Toward a Combination of NIR Photothermal Therapy and Chemotherapy.

ACS applied materials & interfaces·2025
Same author

Synthesis of Precisely Modified Ribonucleic Acid to Reveal the Site-Specific Effect of Modification on Message Ribonucleic Acid Translation.

Journal of the American Chemical Society·2025
Same author

Supertough and Multirecyclable Cross-Linked Polyurethane Enabled by Supramolecular Chain Extenders and Noncovalent Cross-Linkers.

Journal of the American Chemical Society·2025
JoVE
x logofacebook logolinkedin logoyoutube logo
JoVEについて
概要リーダーシップブログJoVEヘルプセンター
著者向け
出版プロセス編集委員会範囲と方針査読よくある質問投稿
図書館員向け
推薦の声購読アクセスリソース図書館諮問委員会よくある質問
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experimentsアーカイブ
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教員リソースセンター教員サイト
利用規約
プライバシーポリシー
ポリシー

関連する実験動画

Updated: Sep 1, 2025

Creating Highly Specific Chemically Induced Protein Dimerization Systems by Stepwise Phage Selection of a Combinatorial Single-Domain Antibody Library
10:17

Creating Highly Specific Chemically Induced Protein Dimerization Systems by Stepwise Phage Selection of a Combinatorial Single-Domain Antibody Library

Published on: January 14, 2020

7.9K

ノンコヴァラント・ダイメリゼーションの分子工学

Guanglu Wu1, Fei Li1, Bohan Tang2

  • 1State Key Laboratory of Supramolecular Structure and Materials, College of Chemistry, Jilin University, Changchun 130012, China.

Journal of the American Chemical Society
|August 15, 2022
PubMed
まとめ

超分子制限を用いたダイマーの分子工学は,材料の性質を高めます. 擬態ジメルは,ダイナミックなシステムでは見られないユニークな崩壊経路と新興特性を提供します.

さらに関連する動画

Chemical Dimerization-Induced Protein Condensates on Telomeres
08:52

Chemical Dimerization-Induced Protein Condensates on Telomeres

Published on: April 12, 2021

3.2K
Synthesis of Information-bearing Peptoids and their Sequence-directed Dynamic Covalent Self-assembly
09:34

Synthesis of Information-bearing Peptoids and their Sequence-directed Dynamic Covalent Self-assembly

Published on: February 6, 2020

7.4K

関連する実験動画

Last Updated: Sep 1, 2025

Creating Highly Specific Chemically Induced Protein Dimerization Systems by Stepwise Phage Selection of a Combinatorial Single-Domain Antibody Library
10:17

Creating Highly Specific Chemically Induced Protein Dimerization Systems by Stepwise Phage Selection of a Combinatorial Single-Domain Antibody Library

Published on: January 14, 2020

7.9K
Chemical Dimerization-Induced Protein Condensates on Telomeres
08:52

Chemical Dimerization-Induced Protein Condensates on Telomeres

Published on: April 12, 2021

3.2K
Synthesis of Information-bearing Peptoids and their Sequence-directed Dynamic Covalent Self-assembly
09:34

Synthesis of Information-bearing Peptoids and their Sequence-directed Dynamic Covalent Self-assembly

Published on: February 6, 2020

7.4K

科学分野:

  • 超分子化学
  • 材料科学
  • 物理化学

背景:

  • 凝縮された相における分子相互作用を理解するための基本的なモデルとして機能する.
  • モノマーと比べると 二次体内の分子相互作用が 独自の性質を決定する.
  • 超分子制限は,非共性二分化とその動態に対する正確な制御を提供します.

研究 の 目的:

  • 非共性ダイマーの分子工学における最近の進歩をレビューする.
  • 超分子制約が分子材料に 強化された機能を与える方法を強調する.
  • 擬態ジマーとそのユニークな特性を紹介する.

主な方法:

  • 超分子二重体,折り畳み二重体,およびマクロサイクル二重体の研究.
  • 異なる超分子制約が材料の性能にどのように影響するかを分析する.
  • 擬態ジマーとその動的適応性についての議論.

主要な成果:

  • エンジニアリングされたダイマーは,放出と室温の光性を強化した性能を示します.
  • 効率的な触媒は,ダイマーに合わせた分子工学によって達成される.
  • 擬態ジメルは 持続的な分子相互作用と適応性を可能にします

結論:

  • 超分子制限による非共性二分化の分子工学は強力な戦略です.
  • 擬態ジメは新興物質特性の新たな経路を提供する.
  • このアプローチは,高度な分子ベースの材料の開発に大きな可能性を秘めています.