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rabindra.tharu.np@gmail.com
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In Vitro and In-Silico Assessment of Gaussian Curvature-driven Internalization Kinetics of Nanoparticles
Nanoparticles have been of significant interest in various biomedical domains such as drug delivery, gene delivery, cytotoxicity analysis, and imaging. Despite the synthesis of a variety of nanoparticles, their cellular uptake efficiency remains a substantial obstacle, with only a small fraction of delivered nanoparticles (NPs) have been reported to traverse the cell membrane within 24…
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rabindra.tharu.np@gmail.com
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Self-Assembled Monolayer Suppresses Interfacial Reaction between NiO(x) and Perovskite for Efficient and Stable Inverted Inorganic Perovskite Solar Cells
Inorganic NiO has attracted tremendous attention in organic-inorganic hybrid perovskite solar cells (PSCs) in recent years but is relatively less used in all-inorganic PSCs. In this study, we have discovered and confirmed the detrimental interfacial reaction between NiO and DMAI-containing CsPbI inorganic perovskites. Thus, a self-assembled monolayer, Br-2PACz, is employed to modify the NiO surface…
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rabindra.tharu.np@gmail.com
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W(18)O(49) Nanofibers Functionalized with Graphene as a Selective Sensing of NO(2) Gas at Room Temperature
Recent trends in two-dimensional (2D) graphene have demonstrated significant potential for gas-sensing applications with significantly enhanced sensitivity even at room temperature. Herein, this study presents fabrication of distinctive gas sensor based on one-dimensional (1D) WO nanofibers decorated 2D graphene, specifically coated on copper (Cu)-based interdigitated electrodes formed by DC sputtering, which can selectively detect NO…
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rabindra.tharu.np@gmail.com
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Zein-Coated Zn Metal Particles-Incorporated Nanofibers: A Potent Fibrous Platform for Loading and Release of Zn Ions for Wound Healing Application
Metal particles incorporated into polymer matrices in various forms and geometries are attractive material platforms for promoting wound healing and preventing infections. However, the fate of these metal particles and their degraded products in the tissue environment are still unknown, as both can produce cytotoxic effects and promote unwanted wound reactions. In this study, we…
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rabindra.tharu.np@gmail.com
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NIR-Responsive Deployable and Self-Fitting 4D-Printed Bone Tissue Scaffold
The treatment of irregular-shaped and critical-sized bone defects poses a clinical challenge. Deployable, self-fitting tissue scaffolds that can be implanted by minimally invasive procedures are a promising solution. Toward this, we fabricated NIR-responsive and programmable polylactide-co-trimethylene carbonate (PLMC) scaffolds nanoengineered with polydopamine nanoparticles (PDA) by extrusion-based three-dimensional (3D) printing. The 3D-printed scaffolds demonstrated excellent (>99%),…
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rabindra.tharu.np@gmail.com
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Constructing the Snail Shell-Like Framework in Thermal Interface Materials for Enhanced Through-Plane Thermal Conductivity
Melioration of the through-plane thermal conductivity (TC) of thermal interface materials (TIMs) is a sore need for efficient heat dissipation to handle an overheating concern of high-power-density electronics. Herein, we constructed a snail shell-like thermal conductive framework to facilitate vertical heat conduction in TIMs. With inspiration from spirally growing calcium carbonate platelets of snail shells,…
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rabindra.tharu.np@gmail.com
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Supramolecular Composite Hydrogel Loaded with CaF(2) Nanoparticles Promotes the Recovery of Periodontitis Bone Resorption
Treatments to reduce periodontal inflammation and rescue periodontitis bone resorption have been of interest to researchers. Bone tissue engineering materials have been gradually used in the treatment of bone defects, but periodontal bone tissue regeneration still faces challenges. Considering the biocompatibility factor, constructing bionic scaffolds with natural extracellular matrix properties is an ideal therapeutic pathway.…
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rabindra.tharu.np@gmail.com
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Multiple RONS-Loaded Plasma-Activated Ice Microneedle Patches for Transdermal Treatment of Psoriasis
Cold atmospheric plasma (CAP) is a fledgling therapeutic technique for psoriasis treatment with noninvasiveness, but clinical adoption has been stifled by the insufficient production and delivery of plasma-generated reactive oxygen and nitrogen species (RONS). Herein, patches of air-discharge plasma-activated ice microneedles (PA-IMNs) loaded with multiple RONS are designed for local transdermal delivery to treat psoriasis…
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rabindra.tharu.np@gmail.com
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Acid-Resistant Nano-antioxidants Based on Epigallocatechin Gallate Alleviate Acute Intestinal and Kidney Inflammation
Epigallocatechin gallate (EGCG)-based nanosystems have garnered significant attention for their ability to alleviate inflammation due to their excellent anti-inflammatory properties and enhanced drug delivery capabilities. However, the degradation of EGCG in strongly acidic environments poses a challenge for potential administration, particularly in oral formulations, where gastric resistance is essential. In this study, we develop a…
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rabindra.tharu.np@gmail.com
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Theoretical Study on the Electrocatalytic CO(2) Reduction Mechanism of Single-Atom Co Complexed Carbon-Based (Co-N(χ)@C) Catalysts Supported on Carbon Nanotubes
Electrocatalytic CO reduction serves as an effective strategy to tackle energy crises and mitigate greenhouse gas effects. The development of efficient and cost-effective electrocatalysts has been a research hotspot in the field. In this study, we designed four Co-doped single-atom catalysts (Co-N@C) using carbon nanotubes as carriers, these catalysts included tri- and dicoordinated N-doped carbon…
