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rabindra.tharu.np@gmail.com
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Fabrication and evaluation of a bi-layered electrospun PCL/PVA patch for wound healing: Release of vitamins and silver nanoparticle
There is still little research on the co-delivery of vitamins and AgNPs to accelerate wound healing. In this study, a bi-layered electrospun PCL/PVA patch loaded with Vitamin C, Vitamin B12, and AgNPs was fabricated using a co-spinning technique. SEM, FTIR, degradation, swelling, tensile strength, disk diffusion, and MTT assay were studied. Nine rats were placed…
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rabindra.tharu.np@gmail.com
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Assessment of breast cancer awareness and detection of asymptomatic cases in Ngaoundere, Adamawa region of Cameroon
INTRODUCTION In Cameroon and most African countries, breast cancer (BC) is mainly diagnosed at an advanced stage, leading to worse prognosis and disease consequences. This is partly due to the delayed presentation of patients, which constitutes a significant barrier to the effective management of the disease. The aim of this descriptive, cross-sectional study is to…
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rabindra.tharu.np@gmail.com
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A BERT-based approach for identifying anti-inflammatory peptides using sequence information
The use of anti-inflammatory peptides (AIPs) as an alternative therapeutic approach for inflammatory diseases holds great research significance. Due to the high cost and difficulty in identifying AIPs with experimental methods, the discovery and design of peptides by computational methods before the experimental stage have become promising technology. In this study, we present BertAIP, a…
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rabindra.tharu.np@gmail.com
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Genotype-by-environment interaction and stability analysis of grain yield of bread wheat (Triticum aestivum L.) genotypes using AMMI and GGE biplot analyses
Bread wheat is a vital staple crop worldwide; including in Ethiopia, but its production is prone to various environmental constraints and yield reduction associated with adaptation. To identify adaptable genotypes, a total of 12 bread wheat genotypes (G1 to G12) were evaluated for their genotype-environment interaction (GEI) and stability across three different environments for two…
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rabindra.tharu.np@gmail.com
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Examination of coronoid foramen and coronoid canal with CBCT
OBJECTIVE This study aimed to examine the coronoid foramen using CBCT not only according to its localization, distribution to gender and age but also to determine whether there are canals associated with the coronoid foramen and to identify them and their clinical significance. METHODS 488 images obtained between 2022 and 2023 were retrospectively evaluated in…
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rabindra.tharu.np@gmail.com
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Forecasting residual mechanical properties of hybrid fibre-reinforced self-compacting concrete (HFR-SCC) exposed to elevated temperatures
The use of hybrid fibre-reinforced Self-compacting concrete (HFR-SCC) has escalated recently due to its significant advantages in contrast to normal concrete such as increased ductility, crack resistance, and eliminating the need for compaction etc. The process of determining residual strength properties of HFR-SCC after a fire event requires rigorous experimental work and extensive resources. Thus,…
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rabindra.tharu.np@gmail.com
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Comparative performance of liquid chromatography and spectrophotometry in determining metformin hydrochloride within pharmaceutical formulations
The present study compared the performance of Ultra-high performance liquid chromatography (UHPLC) and UV-Vis spectrophotometry for the quantification of metformin hydrochloride in five commercially available metformin hydrochloride products with different strengths. The metformin hydrochloride was measured in the UHPLC with a mobile phase consisting of a mixture of 0.05 M phosphate buffer solution and methanol (35:65,…
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rabindra.tharu.np@gmail.com
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Comprehensive molecular analyses and experimental validation of CDCAs with potential implications in kidney renal papillary cell carcinoma prognosis
Previous reports have revealed that the abnormal expression of the cell division cycle-associated gene family (CDCAs) is closely associated with some human cancers. However, the precise functional roles and mechanisms of CDCAs in kidney renal papillary cell carcinoma (KIRP) remain unclear. In this study, RNA sequencing data from the Cancer Genome Atlas database and Genotype-Tissue…
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rabindra.tharu.np@gmail.com
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Improving sunflower growth and arsenic bioremediation in polluted environments: Insights from ecotoxicology and sustainable mitigation approaches
The issue of arsenic (As) contamination in the environment has become a critical concern, impacting both human health and ecological equilibrium. Addressing this challenge requires a comprehensive strategy encompassing water treatment technologies, regulatory measures for industrial effluents, and the implementation of sustainable agricultural practices. In this study, diverse strategies were explored to enhance As accumulation…
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rabindra.tharu.np@gmail.com
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Computational insights into survival durations and prehospital interventions in accidental cold-water immersion: A comprehensive analysis of fresh and saltwater temperatures
This study examines the complex relationship between scenarios of cold-water immersion, survival durations, and prehospital interventions. It utilizes computational modeling methods to shed light on how different water temperatures affect individuals facing accidental cold-water immersion incidents. The analysis reveals significant variations in survival times based on water temperature. For example, subjects immersed in water at…
