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rabindra.tharu.np@gmail.com
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Assessing the causal relationship between CRP, IL-1α, IL-1β, and IL-6 levels and intervertebral disc degeneration: a two-sample Mendelian randomization study
Growing research has suggested an association between chronic inflammation and Intervertebral disc degeneration (IVDD), but whether there is a causal effect remains unknown. This study adopted two-sample Mendelian randomization (MR) approach to explore the etiological role of chronic inflammation in IVDD risk. Here, summary statistics for C-reactive protein (CRP), interleukin (IL)-1 , IL-1 , IL-6…
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rabindra.tharu.np@gmail.com
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A concept of controlling Grover diffusion operator: a new approach to solve arbitrary Boolean-based problems
A controlled-diffusion operator for Boolean oracles is designed as a new approach for Grover’s algorithm to search for solutions for arbitrary logical structures of such oracles, since the Grover diffusion operator is not able to find correct solutions for some logical structures of Boolean oracles. We also show that the Phase oracles do not work…
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rabindra.tharu.np@gmail.com
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Enrichment of shortcrust pastry cookies with bee products: polyphenol profile, in vitro bioactive potential, heat-induced compounds content, colour parameters and sensory changes
Bee products, including bee pollen (BP) and bee bread (BB) are natural sources that contain a diverse range of bioactive compounds. The objective of this study was to investigate the potential of BP and BB to enhance the functional properties of shortcrust pastry cookies. The impact on BP and BB on the colour parameters, polyphenolic…
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rabindra.tharu.np@gmail.com
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Exploring the ability of the MD+FoldX method to predict SARS-CoV-2 antibody escape mutations using large-scale data
Antibody escape mutations pose a significant challenge to the effectiveness of vaccines and antibody-based therapies. The ability to predict these escape mutations with computer simulations would allow us to detect threats early and develop effective countermeasures, but a lack of large-scale experimental data has hampered the validation of these calculations. In this study, we evaluate…
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rabindra.tharu.np@gmail.com
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Enhancing human computer interaction with coot optimization and deep learning for multi language identification
Human-Computer Interaction (HCI) is a multidisciplinary field focused on designing and utilizing computer technology, underlining the interaction interface between computers and humans. HCI aims to generate systems that allow consumers to relate to computers effectively, efficiently, and pleasantly. Multiple Spoken Language Identification (SLI) for HCI (MSLI for HCI) denotes the ability of a computer system…
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rabindra.tharu.np@gmail.com
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The impact of trauma core dimensions on anxiety and depression: a latent regression model through the Post-Traumatic Symptom Questionnaire (PTSQ)
Adverse life events (e.g., severe accidents, violence/abuse, organic disorders) can elicit traumatic responses characterized by intrusive thoughts, hyperarousal, and avoidance-highlighting the need for sound assessment tools. Also, these traumatic components could heighten anxiety and depression symptoms. This study aims included to: (1) assessing the psychometric properties of the Post-Traumatic Symptom Questionnaire (PTSQ) and delineating clinical…
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rabindra.tharu.np@gmail.com
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Short term sodium glucose transport protein 2 inhibitors are associated with post contrast acute kidney injury in patients with diabetes
Although sodium-glucose transport protein-2 (SGLT2) inhibitors (SGLT2i) do not increase the risk of acute kidney injury (AKI) in general, they may pose a risk in patients undergoing angiography. This prospective cohort study aimed to evaluate the safety and efficacy of SGLT2i for post-contrast AKI (PC-AKI) in patients with type 2 diabetes mellitus (T2DM). Following screening,…
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rabindra.tharu.np@gmail.com
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Ameliorating effects of natural herbal supplements against water-borne induced toxicity of heavy metals on Nile tilapia, (Oreochromis niloticus)
The efficacy of herbal supplements in mitigating heavy metals (HMs) toxicity was investigated using a widely grown fish, the Nile tilapia (Oreochromis niloticus). The experiment was conducted over two phases: during the stress phase, the experimental fishes were exposed to sub-lethal concentrations of HMs, including lead, cadmium, zinc, and copper for 15 days; following which during the feeding…
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rabindra.tharu.np@gmail.com
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Efficient DC motor speed control using a novel multi-stage FOPD(1 + PI) controller optimized by the Pelican optimization algorithm
This paper introduces a novel multi-stage FOPD(1 + PI) controller for DC motor speed control, optimized using the Pelican Optimization Algorithm (POA). Traditional PID controllers often fall short in handling the complex dynamics of DC motors, leading to suboptimal performance. Our proposed controller integrates fractional-order proportional-derivative (FOPD) and proportional-integral (PI) control actions, optimized via POA to achieve…
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rabindra.tharu.np@gmail.com
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Phylogenetic position of the pigeon mite, Ornithonyssus sylviarum, with amplification of its immunogenetic biomarkers in Egypt
Ornithonyssus sylviarum (O. sylviarum) is an obligatory, blood-sucking ectoparasite widely distributed among poultry and other mammals, causing significant economic losses. This study represented the first report of molecular genotypic identification of O. sylviarum from pigeons, Columba livia domestica, in Egypt. PCR and sequencing of the 28S rRNA gene were conducted. The resulting mite sequences were…
