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rabindra.tharu.np@gmail.com
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3D printed teeth with adhesive bridge preparation guide
In this study a 3D printed tooth with adhesive bridge preparation guide was designed and tested for feasibility and evaluated by students. The tooth, printed by a stereolithographic printer, consisted of two differently colored layers with an integrated adhesive bridge preparation. This showed the extent and thickness of the preparation. 42 dental students in the…
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rabindra.tharu.np@gmail.com
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Toxoplasma FER1 is a versatile and dynamic mediator of differential microneme trafficking and microneme exocytosis
Toxoplasma gondii is a polarized cell concentrating several secretory organelles at the apical pole. The secretory micronemes come in two sub-populations differentiated by dependence on Rab5A/C in their biogenesis. Calcium-dependent exocytosis of micronemes occurs at the very apical tip and is critical for parasite egress from its host cell, adhesion and invasion of the next…
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rabindra.tharu.np@gmail.com
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Metabolomic and transcriptomic basis of photoperiodic response regulation in broomcorn millet (Panicum miliaceum L.)
To elucidate the mechanisms underlying photoperiodic responses, we investigated the genomic and metabolomic responses of two broomcorn millet (Panicum miliaceum L.) genotypes. For this purpose, light-insensitive (D32) and light-sensitive (M51) genotypes were exposed to a 16 h photoperiod (long-day (LD) conditions) and an 8 h photoperiod (short-day (SD) conditions), and various transcriptomic and metabolomic changes were investigated.…
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rabindra.tharu.np@gmail.com
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C reactive protein albumin ratio as a new predictor of postoperative delirium after cholecystectomy for acute cholecystitis
Postoperative delirium (POD) is one of the most common complications of surgery. This study aimed to identify the risk factors for POD in patients undergoing cholecystectomy for acute cholecystitis. This retrospective study included 77 patients who underwent cholecystectomy for acute cholecystitis between January 2015, and December 2020. Multiple logistic regression analysis was used to identify the…
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rabindra.tharu.np@gmail.com
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Exosomal fragment enclosed polyamine-salt nano-complex for co-delivery of docetaxel and mir-34a exhibits higher cytotoxicity and apoptosis in breast cancer cells
A novel core-shell nanocarrier system has been designed for co-delivery of a small anticancer drug, docetaxel (DTX) and tumor suppressor (TS) miR-34a named as Exo(PAN). The core is formed by pH dependent polyamine salt aggregates (PSA) containing both the payloads and the shell is formed by RAW 264.7 cell derived exosomal fragments. Herein, phosphate driven…
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rabindra.tharu.np@gmail.com
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Investigating the potential of waste glass in paver block production using RSM
The global surge in glass waste generation, exceeding 130 million tons annually, presents a pressing environmental issue, compounded by inadequate recycling practices, it is concerning that the global recycling rate for glass waste is below 50%. This research investigates the utilization of WG as a FA substitute in paver block to mitigate the ecological footprint of…
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rabindra.tharu.np@gmail.com
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Effects of mixed biocrusts on soil nutrients and bacterial community structure: a case study from Hilly Loess Plateau, China
The ecological function of biological crusts in arid and semi-arid areas is of great importance. Bacteria, as a crucial microbial group in biological crusts, play a key role in the formation, nutrient cycling, and regulation of these crusts. However, the succession of biological crusts and the diversity of bacterial communities, along with key environmental factors…
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rabindra.tharu.np@gmail.com
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Efficient removal of ammonia-nitrogen in wastewater by zeolite molecular sieves prepared from coal fly ash
Zeolite molecular sieves are potential adsorbents for wastewater treatment, characterized by high efficiency, simple process, easy regeneration, and low treatment cost. In this study, zeolite A molecular sieves were prepared using coal fly ash (CFA), which is an effective method for the utilization of CFA. The results showed that the CFA-based zeolite molecular sieves synthesized…
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rabindra.tharu.np@gmail.com
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Assessment of the antibacterial and antioxidant activities of seaweed-derived extracts
In swine farming, animals develop diseases that require the use of antibiotics. In-feed antibiotics as growth promoters have been banned due to the increasing concern of antimicrobial resistance. Seaweeds offer bioactive molecules with antibacterial and antioxidant properties. The aim was to estimate the in vitro properties of seaweed extracts: Ascophyllum nodosum (AN), Palmaria palmata (PP), Ulva lactuca…
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rabindra.tharu.np@gmail.com
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The relationship between brain structure volumes, depressive symptoms and body composition in obese/overweight and normal-/underweight women
Depressive symptoms are highly prevalent and heterogeneous in women. Different brain structures might be associated with depressive symptoms and body composition in women with obesity/overweight and normal-/underweight, although the data is limited. The analysis included 265 women from Bialystok PLUS population study, untreated with antidepressive or antipsychotic medications. The subjects underwent brain magnetic resonance imaging…
