-
rabindra.tharu.np@gmail.com
·
Comparison of obesity indicators for predicting cardiovascular risk factors and multimorbidity among the Chinese population based on ROC analysis
To date, the best obesity-related indicators (ORIs) for predicting hypertension, dyslipidaemia, Type 2 diabetes mellitus (T2DM) and multimorbidity are still controversial. This study assessed the ability of 17 ORIs [body mass index (BMI), body fat percentage (BF%), c-index, Clínica Universidad de Navarra-Body Adiposity Estimator (CUN-BAE), a body shape index (ABSI), body adiposity index (BAI), waist…
-
rabindra.tharu.np@gmail.com
·
Weighted gene co-expression network analysis identified GBP2 connected to PPARα activity and liver cancer
Liver cancer is the fourth leading cause of cancer-related deaths with a steadily increasing rate worldwide, as a well-known hallmark of liver cancer, metabolic alterations are related to liposomal changes, a common characteristic of primary liver cancers based on recent lipidomics studies. Peroxisome proliferator-activated receptor α (PPARα) is a ligand-activated transcription factor with important lipid…
-
rabindra.tharu.np@gmail.com
·
Enhancing early Parkinson’s disease detection through multimodal deep learning and explainable AI: insights from the PPMI database
Parkinson’s is the second most common neurodegenerative disease, affecting nearly 8.5M people and steadily increasing. In this research, Multimodal Deep Learning is investigated for the Prodromal stage detection of Parkinson’s Disease (PD), combining different 3D architectures with the novel Excitation Network (EN) and supported by Explainable Artificial Intelligence (XAI) techniques. Utilizing data from the Parkinson’s…
-
rabindra.tharu.np@gmail.com
·
Design and implementation of a universal converter for microgrid applications using approximate dynamic programming and artificial neural networks
This paper introduces a novel design for a universal DC-DC and DC-AC converter tailored for DC/AC microgrid applications using Approximate Dynamic Programming and Artificial Neural Networks (ADP-ANN). The proposed converter is engineered to operate efficiently with both low-power battery and single-phase AC supply, utilizing identical side terminals and switches for both chopper and inverter configurations.…
-
rabindra.tharu.np@gmail.com
·
Physical activity moderated the mediating effect of self-control between bullying victimization and mobile phone addiction among college students
This study aims to investigate the relationship between bullying victimization and mobile phone addiction (MPA) among college students, taking into consideration the mediating role of self-control and the moderating role of physical activity. A self-report survey was administered to college students from 4 universities in Guangxi, Liaoning, and Hunan provinces in China. Participants were asked…
-
rabindra.tharu.np@gmail.com
·
A hybrid residue based sequential encoding mechanism with XGBoost improved ensemble model for identifying 5-hydroxymethylcytosine modifications
RNA modifications play an important role in actively controlling recently created formation in cellular regulation mechanisms, which link them to gene expression and protein. The RNA modifications have numerous alterations, presenting broad glimpses of RNA’s operations and character. The modification process by the TET enzyme oxidation is the crucial change associated with cytosine hydroxymethylation. The…
-
rabindra.tharu.np@gmail.com
·
Investigation of genes involved in scent and color production in Rosa damascena Mill
Rosa damascena Mill., commonly known as the King Flower, is a fragrant and important species of the Rosaceae family. It is widely used in the perfumery and pharmaceutical industries. The scent and color of the flowers are significant characteristics of this ornamental plant. This study aimed to investigate the relative expression of MYB1, CCD1, FLS, PAL,…
-
rabindra.tharu.np@gmail.com
·
Unraveling genotypic interactions in sugar beet for enhanced yield stability and trait associations
The interaction between genotype and environment (GEI) significantly influences plant performance, crucial for breeding programs and ultimately boosting crop productivity. Alongside GEI, breeders encounter another hurdle in their quest for yield improvement, notably adverse and negative correlations among pivotal traits. This study delved into the stability of white sugar yield (WSY), root yield (RY), sugar…
-
rabindra.tharu.np@gmail.com
·
Association between muscle mass and overall survival among colorectal cancer patients at tertiary cancer center in the Middle East
Recent reports have shown that pre-treatment low muscle mass may lead to poorer outcomes for cancer patients. We explored the correlation between Visceral Adipose Tissue (VAT), Subcutaneous Adipose Tissue (SAT), and Muscle Mass (MM) as measured by CT scans, and overall survival (OS) following diagnosis of colorectal cancer (CRC). We conducted a retrospective review of…
-
rabindra.tharu.np@gmail.com
·
Modeling and validation of purification of pharmaceutical compounds via hybrid processing of vacuum membrane distillation
This study provides an in-depth examination of forecasting the concentration of pharmaceutical compounds utilizing the input features (coordinates) r and z through a range of machine learning models. Purification of pharmaceuticals via vacuum membrane distillation process was carried out and the model was developed for prediction of separation efficiency based on hybrid approach. Dataset was…
