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Updated: Jul 13, 2026

Ratiometric Biosensors that Measure Mitochondrial Redox State and ATP in Living Yeast Cells
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Ratiometric Biosensors that Measure Mitochondrial Redox State and ATP in Living Yeast Cells

Published on: July 22, 2013

蛋白质的氧化和衰老

E R Stadtman1

  • 1Laboratory of Biochemistry, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD 20892.

Science (New York, N.Y.)
|August 28, 1992
PubMed
概括

氧自由基对蛋白质的氧化修饰导致酶降解,随着年龄和疾病的增加而增加. 这种与年龄相关的蛋白质损伤可能源于未经修复的DNA损伤,影响蛋白质氧化和降解率.

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