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A Restriction Enzyme Based Cloning Method to Assess the In vitro Replication Capacity of HIV-1 Subtype C Gag-MJ4 Chimeric Viruses
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进化遗传学:CCR5突变和瘟疫保护

Joan Mecsas1, Greg Franklin, William A Kuziel

  • 1Department of Microbiology and Immunology, Stanford University School of Medicine, Stanford, California 94305-5402, USA.

Nature
|February 13, 2004
PubMed
概括

缺乏CCR5可能无法保护人免受风瘟疫. 研究人员用Yersinia pestis感染了正常小鼠和缺乏CCR5的小鼠,结果没有发现差异,这表明突变对这种致命的细菌没有保护.

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