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相关概念视频

Organic Compounds03:02

Organic Compounds

All living things are formed mostly of carbon compounds called organic compounds. The category of organic compounds includes both natural and synthetic compounds that contain carbon. Although a single, precise definition has yet to be identified by the chemistry community, most agree that a defining trait of organic molecules is the presence of carbon as the principal element, bonded to hydrogen and other carbon atoms. However, some carbon-containing compounds such as carbonates, cyanides, and...
Amino acids03:42

Amino acids

Amino acids are the monomers that comprise proteins. Each amino acid has the same fundamental structure, which consists of a central carbon atom, or the alpha (α) carbon, bonded to an amino group (NH2), a carboxyl group (COOH), and to a hydrogen atom. Every amino acid also has another atom or group of atoms bonded to the central atom known as the R group. There are 20 common amino acids present in proteins, each with a different R group. Variation in the amino acid sequence is responsible for...
Peptide Bonds02:43

Peptide Bonds

A peptide bond covalently attaches amino acids through a dehydration reaction. One amino acid's carboxyl group and another amino acid's amino group combine, releasing a water molecule. The resulting bond is the peptide bond. The products that such linkages form are peptides. As more amino acids join this growing chain, the resulting chain is a polypeptide. Each polypeptide has a free amino group at one end. This end has the N-terminal, or the amino-terminal, and the other end has a free...
Protein and Protein Structure02:15

Protein and Protein Structure

Proteins are one of the most abundant organic molecules in living systems and have the most diverse range of functions of all macromolecules. Proteins may be structural, regulatory, contractile, or protective. They may serve in transport, storage, or membranes; or they may be toxins or enzymes. Their structures, like their functions, vary greatly. They are all, however, amino acid polymers arranged in a linear sequence.
A protein's shape is critical to its function. For example, an enzyme can...
Overview of Advanced Functional Groups02:22

Overview of Advanced Functional Groups


Functional groups are groups of atoms with specific chemical properties that occur within organic molecules and are sometimes denoted as “R”. Functional groups can “functionalize” a compound by enabling it to adopt different physical and chemical properties.
Types of Advanced Functional Groups
The table below summarizes some of the major functional groups in organic chemistry.
Carboxylic Acid Derivatives: Overview01:15

Carboxylic Acid Derivatives: Overview

Carboxylic acid derivatives are formed by replacing the hydroxyl group of carboxylic acids with a different functional group. The most common carboxylic acid derivatives are:

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相关实验视频

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A Strategy for Sensitive, Large Scale Quantitative Metabolomics
14:18

A Strategy for Sensitive, Large Scale Quantitative Metabolomics

Published on: May 27, 2014

阿尔法 - 氨基氨基酸的联结体.

Joanna Grundy1, Bruno Donnadieu, François Mathey

  • 1UCR-CNRS Joint Research Chemistry Laboratory, Department of Chemistry, University of California Riverside, Riverside, California 92521-0403, USA.

Journal of the American Chemical Society
|June 15, 2006
PubMed
概括

研究人员从离子和伊米多化物中合成了新型的α-iminoophospholide连接体. 这些连接体与金属化物形成复合体,具有显著的电子移位和独特的结构性质.

科学领域:

  • 有机金属化学 有机金属化学
  • 酸盐化学 酸盐化学
  • 协调化学 协调化学

背景情况:

  • 类离子是有机化学中的多功能核.
  • 伊米多伊尔化物作为电友合作伙伴,形成碳键.

研究的目的:

  • 为了合成新型的α-aminophospholide连接体.
  • 为了探索这些配体与金属化物之间的协调化学.
  • 研究由此产生的复合体的电子和结构性质.

主要方法:

  • 在三氧化物 (tBuOK) 的存在下,离子与伊米多伊尔化物的反应.
  • 分离的三甲基斯坦尼尔衍生物的α-iminophospholides.
  • 与各种金属化物发生复合反应.
  • 密度函数理论 (DFT) 的计算.
  • 一个X射线晶体学.

主要成果:

  • 成功合成alpha-iminophospholides及其三甲基斯坦尼尔衍生物.
  • 形成具有标题连接体的金属复合体.
  • DFT研究揭示了 imino 组和基环之间显著的电子移位.

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  • 斯坦尼尔孔的X射线结构显示了一个高度金字塔式的原子.
  • 一个四度铜复合体在结构上具有特征.
  • 结论:

    • 阿尔法-氨基酸盐是用于协调化学的可访问的配体.
    • 这些配体的电子结构表现出显著的pi-delocalization.
    • 独特的结构特征,包括金字塔式,对于复杂的形成很重要.